Also found in: Medical, Encyclopedia, Wikipedia.
Related to methylation: acetylation


1. An alkylation process involving addition of, or substitution by, a methyl group.
2. The process of treating something with methyl alcohol.
References in periodicals archive ?
Background: DNA methylation has been suggested as a biomarker for early cancer detection and treatment.
The function of genome methylation in invertebrates has only recently been characterized in-depth.
The methylation sensitive amplified polymorphism (MSAP) was used to induce DNA methylation transformation in mushroom mycelia.
2012) reported that maternal smoking during pregnancy was associated with differential DNA methylation in newborns at specific loci that replicated in a second population.
001506) Circulation: Cardiovascular Genetics found that smoking leaves its "footprint" on the genome through DNA methylation, the process by which cells control gene expression.
DNA methylation at CpG dinucleotides is a well-studied epigenetic mechanism, defined as a heritable and enzyme-induced chemical modification of DNA, not altering the DNA sequence (Wu et al.
In a paper published June 20 in the Proceedings of the National Academy of Sciences, scientists examined how a process known as methylation, which can reduce the expression of specific genes, affects a gene called OXT.
They also found evidence that this methylation signature may be present in many more types of cancer.
Part of the solution lies in using DNA methylation as a biomarker for differentiation capacity.
It is known that epigenetic DNA methylation regulates gene expression and is sensitive to the redox environment [5, 11, 12].
Methylation of DNA occurs on cytosines and can be transmitted over many cell generations to sustain epigenetic memory.
7) In addition to differential methylation of the host genome, there is evidence of changes to other epigenetic mechanisms in HPV-positive OPSCCs.