methysergide


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methysergide

(ˌmɛθɪˈsɜːdʒaɪd)
n
(Pharmacology) a drug, C21H27N3O2, used in the form of its maleate to prevent migraines
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La FPR secondaire peut etre le resultat d'un anevrisme de l'aorte, d'une radiotherapie anterieure, d'une chirurgie abdominale, de traumatismes, de tumeurs retroperitoneales primaires ou metastatiques, d'infections (tuberculose, histoplasmose, actinomycose) et de la prise de medicaments (ergotamine, methyldopa, beta-bloquants, methysergide, bromocriptine, hydralazine) (tableau 1).
SOME DRUGS THAT CAN CAUSE OR EXACERBATE HEART FAILURE Condition Drugs Arrhythmia dronedarone, flecainide, disopyramide, sotalol Cancer anthracydines and many other agents Depression citalopram, lithium Diabetes thiazolidinediones, dipeptidyl peptidase-4 inhibitors Fungal infections amphotericin B Hypertension doxazosin, diltiazem, verapamil, moxonidine Malaria chloroquine, hydroxychloroquine Migraines ergotamine, methysergide Pain prescription and nonprescription NSAIDs Parkinson's pergolide, pramipexole, bromocriptine Platelet disorders anagrelide, cilostazol Pulmonary disease bosentan, epoprostenol, albuterol Rheumatologic TNF-a inhibitors diseases
There are isolated reports of ischemic colitis associated with other drugs, like NSAIDs: alosetron (Lotronex, GlaxoSmithKline, Philadelphia, Pennsylvania), used for the management of severe diarrhea in irritable bowel syndrome in women only; pseudoephedrine; interferon; dopamine; and methysergide.
An older clinical trial found that supplementation with 2 to 4 g of L-tryptophan daily was as effective at preventing migraine attacks as the ergot medication methysergide (Sicuteri 1973).
CP-55,940, Naloxone, U-69,593, muscimol, MK801, yohimbine and methysergide were obtained from Tocris Cookson Ltd.
drugs (ergot derivatives, methysergide, bromocriptine, ,[beta]-blockers, methyldopa and hydralazine)
The 5-HT receptor antagonist methysergide inhibited the influence of 5-HT on the overall amount of swimming but not on swimming speed.
PH icin celecoxib (59), rofecoxib (60), asetilsalisilik asit (61), verapamil (61,62,63), acetozolamide (58) topiramate (64,65), steroidler (66) ve buyuk oksipital sinir blokajinin (67) etkili oldugunu bildiren vaka calismalari; HC icin ibuprofen (68), piroxicam (69,70), naproxen (71), rofecoxib (72), celecoxib (73) topiramate (74), gabapentin (75), methysergide, glukokortikoidler, buyuk oksipital sinir blokaji (76), melatonin (77,78), verapamil'in (79) etkili oldugunu bildiren olgular mevcut olsa da; indomethacin kadar tutarli yanit alinan baska bir ajan daha mevcut degildir.
35 Finally, the fact that methysergide, a 5-HT antagonist, can prevent the effects of glucagon provides additional support for the postulation that serotonin, acting at the islet cells directly, is the factor responsible for the above phenomenon.
Case reports also suggest using serotonin receptor antagonists--such as cyproheptadine, methysergide, chlorpromazine, or propranolol--to clinically manage serotonin syndrome, although empiric support is limited.