A Zika virus outbreak in Brazil in 2015 had led to widespread concern after rising incidents of microcephaly
were noticed in children born to mothers infected with the virus.
Recent studies have suggested that risk for microcephaly
is concentrated in pregnancies in which infection occurs during the first trimester (1,2).
Most children born with microcephaly
small head size for age and evidence of congenital Zika virus infection face severe health and developmental challenges at ages 19-24 months, according to results from a new investigation led by the Centers for Disease Control and Prevention (CDC) in collaboration with the State Health Secretariat of Paraba and the Ministry of Health of Brazil.
This paper aims to show data on the demand and grant of the Continuous Cash Benefits for children with microcephaly
in the national territory since 2009.
van der Linden, a pediatric neurologist at the Association for Assistance of Disabled Children in Recife, Brazil, was the lead author of the first report of 13 infants who had laboratory evidence of congenital Zika infection and normal head circumference at birth but who developed poor head growth and microcephaly
later in infancy.
Months later, a growing number of infants in Brazil were born with a serious birth defect: microcephaly
Common clinical features are growth retardation, intellectual disability, delayed psychomotor development, microcephaly
, and dysmorphic facial features.
M2 PHARMA-April 20, 2017-US CDC Research Shows Replication of Zika Virus in Brains of Infants with Microcephaly
and Placentas of Women with Pregnancy Losses
A second study of pregnant women in the USA who had been infected with Zika virus revealed that only 6% had Zika associated defects, but the rates of microcephaly
remained the same as those in Brazil.
The disease was first identified in the World Health Organization's Region of the Americas in 2015 and was followed by a surge in reported cases of congenital microcephaly
in Brazil; Zika virus disease rapidly spread to the rest of the region and the Caribbean (1), including Haiti.
The Department of Health (DOH) added that the baby girl's microcephaly
was not caused by the Zika virus as they first suspected.
Published in December in Emerging Infectious Diseases, the study found that Zika virus RNA remained in fetal brains and placentas for more than seven months after a woman contracted the virus, with evidence that the mosquito borne virus replicated itself in an infant with microcephaly
who died a few months after birth.