microglia


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Related to microglia: Astrocytes, Oligodendrocytes

mi·cro·gli·a

 (mī′krō-glē′ə, -glī′-)
pl.n.
Small neuroglial cells of the central nervous system that have long processes and act as phagocytes at sites of neural damage or inflammation, destroying pathogens and damaged cells.

mi′cro·gli′al adj.

microglia

(ˌmaɪkrəʊˈɡlɪə)
n
(Anatomy) one of the two types of non-nervous tissue (glia) found in the central nervous system, having macrophage activity. Compare macroglia
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.microglia - neuroglial tissue of mesodermal origin that can become phagocyticmicroglia - neuroglial tissue of mesodermal origin that can become phagocytic
glia, neuroglia - sustentacular tissue that surrounds and supports neurons in the central nervous system; glial and neural cells together compose the tissue of the central nervous system
microgliacyte - a cell of the microglia that may become phagocytic and collect waste products of nerve tissue
References in periodicals archive ?
The brain's immune cells, known as microglia, are involved in the brain's normal inflammatory response to trauma or injury, but too much inflammation is associated with other degenerative illnesses as well as depression.
A particular type of macrophage known as microglia are found throughout the brain and spinal cord--in progressive forms of MS, they attack the CNS, causing chronic inflammation and damage to nerve cells.
These differences may be driven by the NLRP3 gene, which, in the presence of neuronal insults such as beta-amyloid aggregates, can direct microglia to pump out a stew of inflammatory cytokines and chemokines, Dr.
M2 PHARMA-February 1, 2018-Eisai to Collaborate with Boston University School of Medicine to Study Effects of Alzheimer's Disease-associated Genetic Variants on Microglia
Experiments found that by destroying specific cells, known as microglia, they reduced the formation of clumps of amyloid beta that cause memory loss.
Immune cells called microglia activate as part of the bodys inflammatory response, so the researchers used a brain imaging technique to measure a substance that increases in activated microglia.
Peripheral nerve injury triggers activation of microglia and astrocytes in the spinal cord.
To examine changes in glial cells in the CA1 following TGCI, immunohistochemistry for astrocytes and microglia was performed using mouse anti-glial fibrillary acidic protein (GFAP, 1:800, Chemicon) and rabbit anti-ionized calcium binding adapter molecule 1 (Iba-1, 1:800, Wako), respectively, according to the above-mentioned method.
These genes reinforce a critical role for special cells in the brain - called microglia - that are responsible for clearing up debris including damaged cells and proteins.
The cells are called microglia and the approach may avoid many side effects of current therapies.
May 18, 2017 -- Scientists here have developed a robust, efficient method for deriving microglia, the immune cells of the brain, from human stem cells.
May 18, 2017 -- Scientists here have developed a robus , efficient method for deriving microglia, the immune cells of the brain, from human stem cells.