microsome


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Related to microsome: microsomal enzymes

mi·cro·some

 (mī′krə-sōm′)
n.
A small particle in the cytoplasm of a cell, typically consisting of fragmented endoplasmic reticulum to which ribosomes are attached.

mi′cro·so′mal (-sō′məl), mi′cro·so′mic (-sō′mĭk) adj.

microsome

(ˈmaɪkrəʊˌsəʊm)
n
(Biology) any of the small particles consisting of ribosomes and fragments of attached endoplasmic reticulum that can be isolated from cells by centrifugal action
ˌmicroˈsomal adj

mi•cro•some

(ˈmaɪ krəˌsoʊm)

n.
a small vesicle containing fragments of ribosomes and other organelles, formed during cell breakage by centrifugation.
[1880–85]
mi`cro•so′mal, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.microsome - a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNAmicrosome - a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA
cytol, cytoplasm - the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism
granule - a tiny grain
Translations

mi·cro·some

n. microsoma, elemento fino granular del protoplasma.
References in periodicals archive ?
Each of the seven CYP Silensomes HLM are packaged as Silensomes CYP Phenotyping Kits to include a production-matched control microsome that was treated the same way without the inhibitor.
c'est la violence des rapports sociaux dans ce microsome infernal que sont les milieux de la finance.
Salmonella / microsome fluctuation test (Ames fluctuation test).
A number of metabolites have been isolated and identified from mixtures generated by either human or rat liver microsome preparations, or isolated from plasma samples or urine.
However, the distribution among the organelle fraction is clearly different as in the cuttlefish 52% was bound to the nuclei fraction whereas in the squid, 42% was bound to the microsome fraction.
Using state-of-the-art technologies such as liver microsome testing and Caco2 cell absorption, and high-speed analytical techniques like LC/MS/MS, this triumvirate of services provides key metabolic and pharmacokinetic data used by companies as lead optimization tools.
There are many negative results on the effects of natamycin, in that some of these reports suggest that natamycin do not induce mutation and it is not clastogenic and mutagenic in various test systems such as Salmonella/mammalian microsome mutation assay in Salmonella typhimurium, Escherichia coli strains, in a mouse lymphoma mutation assay, in chromosome aberration assay with CHO cells (Cox et al.
The method is based on measurement of the concentration of formaldehyde produced by oxidative N-demethylation of amidopyrine in microsome.
In mouse NIH 3T3 L1 preadipocyte cells, TBMEHP inhibited rat hepatic microsome deiodinase activity and was an agonist for PPARs in murine FAO and NIH 3T3 L1 cells.