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A synthetic steroid, C29H35NO2, that blocks the action of progesterone and is used in combination with misoprostol to induce abortion in early pregnancy. Also called RU 486.

[(a)mi(no) + alteration of phe(nyl) + pr(opyl) + alteration of est(radiol) + -one.]


(Pharmacology) an antiprogestogenic steroid, used in the medical termination of pregnancy. Formula: C29H35NO2
[C20: from aminophenol + propyne + oestradiol + -one]


(ˌmɪf əˈprɪs toʊn)
an antigestational drug that prevents a fertilized egg from attaching to the uterine wall by blocking the action of progesterone.
[1985–90; probably alter. of (a)mi(no)phe(nol) + pr(opyl) + est(radiol) + -one]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mifepristone - an abortion-inducing drug (trade name RU_486) developed in Francemifepristone - an abortion-inducing drug (trade name RU_486) developed in France; when taken during the first five weeks of pregnancy it blocks the action of progesterone so that the uterus sloughs off the embryo
aborticide, abortifacient, abortion-inducing drug - a drug (or other chemical agent) that causes abortion


n mifepristona
References in periodicals archive ?
While "Exploring the feasibility of obtaining mifepristone and misoprostol from the internet" has the trappings of a serious study, in fact, it lacks data, controls, or concern for the women who would be taking the two drugs at home without a prescription and without medical supervision of any kind.
The drugs used were mainly mifepristone (RU 486), a potent antiprogestin in combination with prostaglandin [E.
The Arkansas law is based on a controversial method of stopping the effects of a medication abortion by flooding a woman's body with progesterone after she has taken mifepristone, the first of two drugs to trigger pregnancy termination.
The upcoming study builds on a case series he published in 2012 showing that four of six women who took mifepristone carried their pregnancies to term after receiving 200 mg of intramuscular progesterone (Ann Pharmacother.
Objective: To evaluate the clinical therapeutic effects of mifepristone combined with gestrinone on patients with endometriosis.
It was early morning on July 19,1996, and four NWHN colleagues and I were on the way to attend the FDA Advisory Committee meeting about mifepristone (known as "RU 486" or the "French abortion pill").
Mifepristone (RU 486) is a steroid hormone with a chemical structure similar to natural hormone progesterone.
Other revisions to the original FDA label for medication that induces abortions include a lower dosage of the drug, known as mifepristone.
The protocol was oral administration of mifepristone and misoprostol for the patients with the gestational ages below 16 weeks or intra-amniotic injection of ethacridine lactate (EL) for those with at least 16 weeks of gestational ages.
The medications which are widely used are methotrexate, mifepristone and misoprostol [5].
In the past decade, five states have passed laws prohibiting the off-label use of the abortion-inducing drug mifepristone.
In the case of mifepristone and levonorgestrel emergency contraception (Plan B), the agency's mechanisms were used to impede and stall, rather than facilitate, availability.