miglitol


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mig·li·tol

 (mĭg′lĭ-tôl′)
n.
A drug, C8H17NO5, that reduces blood glucose levels by inhibiting the breakdown of complex carbohydrates in the intestine and is used to treat type 2 diabetes.

[(i)mi(ne) + alteration of gly(cemic) + -it(e) + -ol.]
References in periodicals archive ?
Alpha-glucosidase inhibitors (AGIs), such as acarbose (Precose) and miglitol (Glyset), block the absorption of ingested carbohydrates in the small intestine.
The two agents is this subclass are acarbose (Precose) and miglitol (Glyset).
In addition to diet and lifestyle, pharmaceutical molecules including sulfonylureas (which stimulate insulin release) and carbohydrate enzyme inhibitors, like acarbose and miglitol, are used in monitoring type-2 DM.
A modest weight loss was associated with acarbose, exenatide, liraglutide, metformin, miglitol, and pramlintide.
More interestingly, 1,2-O-isopropylidene-a-D-glucofuranose obtained from the hydrolysis of 1,2:5,6-di-O-isopropylidene-a-D-glucofuranose is often used to synthesize medicinal products such as 1-deoxynojirimycin and miglitol [6].
Miglitol and Acarbose both delay the digestion of carbohydrates in the body, also with very minimal side-effects.
Farxiga[R]) Alpha-glucosidase Acarbose Blocks the breakdown inhibitors (Precose[R]) of starches in the Miglitol intestine and may slow (Glyset[R]) the breakdown of other sugars.
miglitol [Glyset[R]], acarbose [Precose[R]]) delay the absorption of carbohydrates by inhibiting conversion of oligosaccharides to monosaccharides in the intestine and thus lower postprandial blood glucose and insulin concentration (ADA, 2015).
Oiso, Y The alpha-glucosidase inhibitor miglitol affects bile acid metabolism and ameliorates obesity and insulin resistance in diabetic mice.
1 While acarbose was first developed in Germany, and later approved the world over, including USA, voglibose is a Japanese invention, while miglitol is an American discovery.
Acarbose, Voglibose and Miglitol have not widely been used to treat type 2 DM individuals but are likely to be safe and effective.