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Any of a group of antibiotics produced by the soil actinomycete Streptomyces caespitosus that inhibit DNA synthesis and are used against bacteria and cancerous tumor cells.

[Probably mito(sis) + -mycin.]


(Pharmacology) pharmacol any of the antibiotics that come from Streptomyces caespitosus
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mitomycin - a complex of antibiotic substances obtained from a streptomyces bacterium; one form (trade name Mutamycin) shows promise as an anticancer drug
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
References in periodicals archive ?
Amniotic membrane graft for primary pterygium: comparison with cojunctival autograft and topical mitomycin C treatment.
As local allergy of the bladder due to direct contact with the allergen is rare (only mitomycin C or thiotepa reported), it is presumed that EC may be part of the tissue eosinophilic infiltration disease.
Furthermore, the use of mitomycin C, aggressive and early repeat dilations, and serial steroid injection might have helped our patient's outcome.
Taxotere, Breast cancer, Docetaxel,Sales forecast, Taxane/ Mitotic Inhibitor, Phase III, Phase 3, Pipeline, competitors to doxorubicin, mitomycin, epirubicin, paclitaxel, Abraxane, Sanofi Aventis, Branded Generics, Intravenous drug, Chemotherapy
20) They retrospectively examined the timing of first mitomycin C (MMC) instillation in patients who received a total of 5 instillations of MMC followed by BCG or interferon-[alpha]2b/BCG therapies, using data from a prospective randomized trial.
Safianik B, Ben-Zion I, Garzozi HJ: Serious corneoscleral complications after pterygium excision with mitomycin C.
Amniotic membrane graft for primary pterygium; comparison with conjunctivalautograft and topical mitomycin c treatment.
Current treatments for non-muscle invasive bladder cancer (NMIBC) involve surgical removal of the tumors via cystoscopy, usually followed by treatment with BCG immunotherapy or chemotherapy with mitomycin C.
An individual patient data meta-analysis of the longterm outcome of randomised studies comparing intravesical mitomycin C versus bacillus Calmette-Guerin for non-muscle-invasive bladder cancer.
DISCUSSION: In our series, we studied role of PRK in treating high myopia along with use of Mitomycin C.
Key Words: Central macular thickness, Mitomycin C, Primary open-angle glaucoma, Pseudoexfoliative glaucoma Kaynaklar