modifier gene


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Related to modifier gene: recessive epistasis, epistatic
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Noun1.modifier gene - a gene that modifies the effect produced by another genemodifier gene - a gene that modifies the effect produced by another gene
cistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
References in periodicals archive ?
Reduced penetrance is probably the result of modifier genes that are present elsewhere in the genome, and which can now be more easily identified because of the HGP and ENCODE; in turn, these modifier genes can be used to increase predictive precision in the form of modifier gene-complemented monogenic diagnostic tests.
Considering all data, human homologous of Bop gene (BOP) seems to be candidate modifier gene for HCMP in which both cardiac hypertrophy and cardiac contraction have central role.
However, they reported a candidate locus for a nuclear modifier gene associated with the mtDNA A1555G mutation in a same family using nonparametric analysis.
The researchers also point out that previous mouse studies have implicated the modifier gene on chromosome 4 in audiogenic seizures, another form of epilepsy.
We are pleased with the accomplishments we have achieved in the past several months, including the augmentation of the ISV-900 program through the licensing of a TIGR modifier gene and the OCLM gene from INSERM of France and Dr.
According to the authors of the study, each of the gene loci they have identified represents a candidate for a human modifier gene in patients with FVL and other thrombophylic mutations.
Grossman of the University of Texas Health Sciences Center at Dallas and his colleagues have located the modifier gene on human chromosome 2.
Garchon at INSERM to continue his research on the clinical applications of the TIGR gene and the newly discovered modifier gene to glaucoma.