modifier gene


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Related to modifier gene: recessive epistasis, epistatic
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Noun1.modifier gene - a gene that modifies the effect produced by another genemodifier gene - a gene that modifies the effect produced by another gene
cistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
References in periodicals archive ?
The authors found MEFV as a susceptibility and modifier gene in BD.
Because each set of iPSCs is specific to the individual from whom they arc derived, researchers can compare the sets to identify molecular differences, such as a modifier gene active in one person but not the other.
Reduced penetrance is probably the result of modifier genes that are present elsewhere in the genome, and which can now be more easily identified because of the HGP and ENCODE; in turn, these modifier genes can be used to increase predictive precision in the form of modifier gene-complemented monogenic diagnostic tests.
Considering all data, human homologous of Bop gene (BOP) seems to be candidate modifier gene for HCMP in which both cardiac hypertrophy and cardiac contraction have central role.
However, they reported a candidate locus for a nuclear modifier gene associated with the mtDNA A1555G mutation in a same family using nonparametric analysis.
Indeed, when evolving populations become fixed for adaptive and ameliorative mutations, distinction between allele replacement and modifier gene occurrences is no longer possible, unless a genetic survey of the population is continuously conducted.
Because each set of iPSCs is specific to the individual from whom they are derived, researchers can compare the sets to identify molecular differences, such as a modifier gene active in one person but not the other.
Thus, this modifier gene is of a qualitatively different character than that used in the study of the evolution of recombination, mutation, or migration (Feldman 1972; Feldman et al.
The researchers also point out that previous mouse studies have implicated the modifier gene on chromosome 4 in audiogenic seizures, another form of epilepsy.
We are pleased with the accomplishments we have achieved in the past several months, including the augmentation of the ISV-900 program through the licensing of a TIGR modifier gene and the OCLM gene from INSERM of France and Dr.
1998) reported that one major gene and one modifier gene were responsible for conditioning of reduced palmitic acid content in N87-2122-4.