molecular chaperone


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Related to molecular chaperone: Chaperone molecule

molecular chaperone

n.
References in periodicals archive ?
9) Furthermore, BiP/GRP78 was found to be a member of the heat shock protein 70 family, whose emerging role at that time was as a molecular chaperone.
Hsp90 the molecular chaperone is capable of binding nuclear receptor and steroid hormone receptor as well as binding severalprotein kinases molecular (including tyrosine protein kinase and serine/threonine kinase in the signal transduction pathway) regulating their bioactivity and participating in a range of life processes such as mitosis immunity or signal transduction (Pearl and Prodromou 2000; Picard 2002; Pratt and Toft 2003; PACopyrightroval et al.
HSP90 exerts its molecular chaperone activity by conformational cycles of binding and release which are dependent upon its ATPase activity.
Hsp90 is an abundant and highly specialized molecular chaperone that plays many important roles in human biology and medicine.
Ahmed Chadli, a researcher in the Molecular Chaperone Program at the GRU Cancer Center and senior author of the study.
A molecular chaperone briefly accompanies its substrate protein and makes sure that the substrate makes no inappropriate inter- and intramolecular interactions," writes Witt (biochemistry and molecular biology, Louisiana State University Health Sciences Center) in his introduction.
They are believed to be involved in the initiation step of translation at high temperature and possibly a molecular chaperone.
In the future the experiments will also explore the molecular method of action of ionomycin, whether it is a pore or a molecular chaperone, and measure the change metabolic activity of the cells once exposed to ionomycin.
Molt cycle-dependent molecular chaperone and polyubiquitin gene expression in lobster.
This lens specific expression and lack of heat shock induction suggests that zebrafish alpha crystallin plays less of a role as a molecular chaperone than its mammalian orthologue.
Like an overprotective human caretaker, the molecular chaperone needs a nudge before it lets go.

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