molecular profiling


Also found in: Medical.

molecular profiling

n.
The identification and documentation of the structure of a specific DNA, RNA, or protein molecule, usually for the purpose of diagnosing biochemical and genetic disorders.
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Berthold G|ttgens, the Universtity of Cambridge, identified the role of Mesp1 in the earliest step of cardiovascular lineage segregation by single cell molecular profiling and lineage tracking.
a privately held, nanotechnology company developing novel solutions for non-invasive detection, molecular profiling, and treatment of cancers and other diseases, announced today that it has been awarded $300,000 by the National Cancer Institute of the National Institutes of Health (NIH) through the Small Business Technology Transfer (STTR) program to enhance the therapeutic efficacy of photodynamic therapy (PDT) in oral cancers.
The protocol will require patients to undergo a tumour biopsy that the Glasgow Precision Oncology Laboratory, within the University of Glasgow, will then use for molecular profiling.
Bioclavis is a new spin-out from Californian molecular profiling company Biospyder, to be based at the Clinical Innovation Zone at Glasgows Queen Elizabeth University Hospital, creating 43 new jobs.
Headquartered in Carlsbad, California, Genoptix provides oncologists and pathologists across the United States with testing solutions in hematology and solid tumor molecular profiling.
Sarah Cannon said by joining forces, the two companies intend to harness and use molecular profiling data to more effectively match cancer patients to cutting-edge therapies in clinical trials.
Investigators will employ new molecular profiling technologies and big data analytics to understand how vascular dysfunction influences the development of Alzheimer's.
WuXi has seen rapidly increasing demand for molecular profiling services from biopharmaceutical companies as they scale up R&D operations and early development activities in the region.
They discuss smoking prevention and cessation, lung cancer susceptibility and risk assessment models, molecular profiling, somatic genome alterations, serum proteomic biomarkers, the molecular biology of lung preneoplasia, the detection and treatment of preneoplastic lesions, the pathology of adenocarcinoma, the management of multifocal bronchioloalveolar carcinoma, radiology and screening, imaging, staging, and the management of the solitary pulmonary nodule.
Laboratory professionals can make use of advanced molecular profiling technologies to help clinicians identify biomarkers in patients' tumors that are predictive of response (or non-response) to specific chemotherapeutic regimens.
Another breakthrough in the field of clinical oncology that will be made possible through molecular profiling is the introduction of a new era of "molecular subclassification" of cancer.
Currently available targeted therapies, diagnostic assays used in clinical laboratories for molecular profiling of tumors, and morphologic-molecular correlations are part of 21st century pathology.

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