monoamine neurotransmitter


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Noun1.monoamine neurotransmitter - a monoamine that is functionally important in neural transmission
noradrenaline, norepinephrine - a catecholamine precursor of epinephrine that is secreted by the adrenal medulla and also released at synapses
5-hydroxytryptamine, serotonin - a neurotransmitter involved in e.g. sleep and depression and memory
dopamine, Dopastat, Intropin - a monoamine neurotransmitter found in the brain and essential for the normal functioning of the central nervous system; as a drug (trade names Dopastat and Intropin) it is used to treat shock and hypotension
monoamine - a molecule containing one amine group (especially one that is a neurotransmitter)
References in periodicals archive ?
Taken together those findings, we suggest that the antidepressant-like action of mitragynine might be through the restoration of monoamine neurotransmitter levels including serotonin, noradrenaline and dopamine in mice.
Despite the significant public health burden of these illnesses and decades of active pharmaceutical research, existing treatments almost exclusively target the monoamine neurotransmitter systems.
Each monoamine neurotransmitter has its own receptors, transporter molecules, storage vesicles and associated signalling pathways but, because they share similar molecular structures, drugs targeting one type of monoamine will also affect others in varying degrees.
Our findings represent the first identification of a residue in monoamine neurotransmitter transporters whose substitution results in the partial or complete uncoupling of ion binding from substrate translocation and may lead to a fundamental understanding as to how the drug "ecstasy" and the interacting protein syntaxin 1A modulate SERT function.
When investigating CSF for a possible defect in monoamine neurotransmitter metabolism, it is critical that one also examine CSF concentrations of the cofactor BH4 and its precursor neopterin.
For example, monoamine neurotransmitter medications are currently under development and are designed to correct an imbalance of monoamines (chemicals used by brain cells to communicate); research suggests that monoamines play a major role in depression.
This increase in monoamine neurotransmitter concentrations results in increased binding at postsynaptic receptors.
In order to flourish in this harsh environment, new antidepressants must be sufficiently differentiated from conventional monoamine neurotransmitter reuptake inhibitors.
A 16-module online course about the management of monoamine neurotransmitter disease and of neurotoxins according to the Bundle Damage Theory.
Presentation, diagnosis, and treatment of disorders of monoamine neurotransmitter metabolism.