monoamine oxidase inhibitor


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Related to monoamine oxidase inhibitor: SSRI, Selegiline, monoamine oxidase inhibitor diet

monoamine oxidase inhibitor

n. Abbr. MAOI
Any of a class of antidepressant drugs that block the action of monoamine oxidase in the brain, thereby allowing the accumulation of monoamine neurotransmitters such as norepinephrine and serotonin.

monoamine oxidase inhibitor

n
(Biochemistry) biochem an agent that inhibits the action of monoamine oxidase. Such inhibitors are used in the treatment of depression. Abbreviation: MAOI

mon′oamine′ ox′idase inhib`itor


n.
any of various substances that block enzymatic breakdown of certain monoamine neurotransmitters and that are used to treat depression. Abbr.: MAOI
[1960–65]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.monoamine oxidase inhibitor - any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulatemonoamine oxidase inhibitor - any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate
antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects
iproclozide - an antidepressant drug that acts as a monoamine oxidase inhibitor
isocarboxazid, Marplan - a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression
Nardil, phenelzine - monoamine oxidase inhibitor (trade name Nardil) used to treat clinical depression
tranylcypromine - an antidepressant drug that is a monoamine oxidase inhibitor; administered as a sulfate
References in periodicals archive ?
Monoamine oxidase inhibitors (MAOIs) have well-established efficacy for treating depression, panic disorder, and social phobia.
In addition, in order to evaluate suspected alterations in the monoaminergic system, we investigated behavioral responses to tranylcypromine (Tcy), a monoamine oxidase inhibitor.
The antidepressants, mood lifting drugs, fall into three main groups: the tricyclics, the "atypical" (or second generation) group, and the monoamine oxidase inhibitors (MAOI).
Treatment of tricyclic refractory depression with a monoamine oxidase inhibitor antidepressant.
In a survey of psychiatrists with AIDS expertise, the top choices for first-line treatment of depression in patients with HIV who had not yet started antiretrovirals were desipramine, amitriptyline, fluvoxamine, or a monoamine oxidase inhibitor, Dr.
The agent is a selective monoamine oxidase inhibitor (MAOI).
ZUTRIPRO([TM]) Oral Solution is contraindicated in individuals with hypersensitivity to hydrocodone, pseudoephedrine HCl, chlorpheniramine, or any of the inactive ingredients; individuals receiving monoamine oxidase inhibitor (MAOI) therapy or within 14 days of stopping such therapy; and individuals with narrow angle glaucoma, urinary retention, severe hypertension or severe coronary artery disease.
The recent approval of an irreversible monoamine oxidase inhibitor for treating Parkinson's disease includes an indication for patients with early disease as well as for those with more advanced disease who are already on levodopa.
The major Parkinson's disease growth driver over the 2005-09 period was the dopamine agonist class, which accounted for nearly half the Parkinson's disease market sales, supported by the continued uptake of the newer catechol-O-methyltransferase (COMT) inhibitor and monoamine oxidase inhibitor (MAOI) classes.
It should not be prescribed for patients with arteriosclerosis, symptomatic heart disease, moderate to severe hypertension, hyperthyroidism, seizures, glaucoma, agitated states, a history of substance abuse problems, a known allergy or unusual reactions to sympathomimetic amines, or for patients who have taken a monoamine oxidase inhibitor in the previous 14 days.
The Food and Drug Administration's approval of a transdermal patch containing selegiline, an irreversible monoamine oxidase inhibitor, for treating major depression could bring much-needed help to the large population of patients that has not responded to uptake inhibitors.
Transdermal selegiline may make it possible to achieve the antidepressant efficacy of a monoamine oxidase inhibitor without the dietary restrictions and acute hypertensive risks that have been largely responsible for the fall from favor of this drug class, Dr.