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Related to monovalent: monovalent vaccine


1. Immunology
a. Containing antigens from a single strain of a microorganism or virus. Used of a vaccine or serum.
b. Having only one site of attachment. Used of an antibody or antigen.
2. Chemistry Univalent.

mon′o·va′lence, mon′o·va′len·cy n.


(Chemistry) chem
a. having a valency of one
b. having only one valency
ˌmonoˈvalence, ˌmonoˈvalency n


(ˌmɒn əˈveɪ lənt)

a. containing only one kind of antibody.
b. pertaining to an antibody fragment with one antigen-binding site.
mon`o•va′lence, mon`o•va′len•cy, n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.monovalent - containing only one kind of antibody
immunology - the branch of medical science that studies the body's immune system
polyvalent - containing several antibodies each capable of counteracting a specific antigen; "a polyvalent vaccine"
2.monovalent - having a valence of 1
chemical science, chemistry - the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions
multivalent, polyvalent - having more than one valence, or having a valence of 3 or higher
References in periodicals archive ?
Phase I/II clinical trials of the bivalent forms of AIDSVAX have demonstrated that the second-generation, bivalent vaccines, like the earlier monovalent vaccine, are safe for use in humans and induce a strong immune response.
Onartuzumab, an investigational monovalent (one-armed) monoclonal antibody designed to specifically target the MET receptor, is being studied in various cancers.
The trial was designed to assess safety and immunogenicity following intramuscular vaccination with needle and syringe or with the Biojector(R) 2000 needle-free injection system in different cohorts, and to evaluate monovalent and trivalent Vaxfectin(R)-formulated DNA vaccines at various doses.
We have shown that a monovalent construct using PADRE effectively induces a long-lived IgG antibody response," said senior author Dr.
Delivery of towing vehicles (aircraft ground equipment) with about 4 tons dead weight, monovalent natural gas drive with about 60 to 70 kW drive power, exhaust system with catalyst for building operation, single cabin, auxiliary loading area (approximately 1.
Food and Drug Administration (FDA) has approved its pandemic Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted (also referred to as Q-Pan H5N1 influenza vaccine) for the immunisation of adults 18 and older for the prevention of disease caused by the influenza A virus H5N1 subtype contained in the vaccine.
The study showed that when all three seasonal influenza VLPs were given as a single trivalent vaccine, the immune response to each subtype was comparable to that observed when the VLPs were given in a monovalent formulation.
The authors provide an introduction to the various models of these chemical shifts before discussing the specific mechanisms for hydrocarbons, aromatics, monovalent substituents and divalent substituents.
The data we present show the monovalent binding to normal cells of other
A protest was recently published against the WHO and its organ the National Polio Surveillance Project (NPSP), for experimenting on human subjects without their consent, a new monovalent oral polio vaccine (mOPV1) that was 5 times stronger than the earlier licensed mOPV (14,15).
chrysogenum usually contained high concentrations of phosphate as well as other monovalent cations [10], such as ammonium and sodium, the effects of these monovalent cations on Ca-, Ba- and Sr-alginate gel matrices were investigated in order to produce a modified defined medium for immobilized cells.