The program will concentrate on increasing the breadth of coverage induced by optimized SynCon vaccines by exploring the potential of a multivalent
DNA vaccine targeting multiple TB antigens at both active and latent stages of infection.
Genisphere provides the 3DNA platform, a nanoscale, multivalent
scaffold made from proprietary, synthetic DNA formed in a flexible, branched structure, for targeted drug delivery.
This CARB-X award will help us complete the preclinical studies and the Phase I clinical trial for IBT-V02, the first entirely toxoid-based multivalent
vaccine for prevention of infections with Staphylococcus aureus," said Dr.
According to Genisphere LLC, 3DNA is a nanoscale, multivalent
scaffold made from proprietary, synthetic DNA formed in a flexible, branched structure.
More recently, Baxter Bioscience developed a second-generation multivalent
vaccine against LB with a purpose of global application.
Collabody is a unique recombinant protein engineering platform, which utilizes a short triplex-forming collagenous peptide, derived from human serum collagens to make multivalent
This platform is synergistic with Zymeworks' Azymetric, AlbuCORE, and EFECT technologies and will enable the design of highly targeted and potent bi-specific antibodies and multivalent
protein therapeutics across a range of indications.
Among Todorov's achievements they highlighted were all the investments in reconstruction of present and construction of new health facilities, the procurement of modern medical equipment, the cutting of prices of medicines, the bringing of health services closer to rural areas, and the introduction of multivalent
01 wt % to about 5 wt % of a multivalent
salt to form the superabsorbent polymer containing hydrous kaolin particulate.
U.S. Patent No. 8,962,910 B2: superabsorbent polymer containing clay particulate, and method of making same: Michael M. Azad, Reidsville, NC; Scott J. Smith, Greensboro, NC; Mark Joy, Reidsville, NC; Geoffrey Wyatt Blake, Kernersville, NC; and Michael S. Jarman, High Point, NC
The grant will fund a project entitled IMMUNOSHAPE which aims to train a new generation of scientists capable of applying state of the art synthesis and screening technology to develop new lead structures for highly selective glycan based multivalent
immunotherapeutics for the treatment of cancer, autoimmune diseases and allergy.
It cannot be solved by government alone because of the multivalent
nature of this crime, which is carried out through internet service providers and transacted using financial institutions, and which needs to be combated with effective information campaigns in schools, churches, and media.
US) write in their introduction, about the "set of propositions about affect, agency, circulation, and spectatorship implied by the multivalent
, troubling notion of 'images that move'" through both space and time.