Also found in: Thesaurus, Medical, Legal, Encyclopedia, Wikipedia.


Formation or development of a mutation.


(Genetics) genetics the generation, usually intentional, of mutations
[C20: from mutation + -genesis]


(ˌmyu təˈdʒɛn ə sɪs)

the origin and development of a mutation.
mu`ta•ge•net′ic (-dʒəˈnɛt ɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mutagenesis - an event capable of causing a mutation
cause - events that provide the generative force that is the origin of something; "they are trying to determine the cause of the crash"
chromosomal mutation, genetic mutation, mutation - (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism
insertional mutagenesis - (genetics) a mutation caused by the insertion of exogenous DNA into a genome
References in periodicals archive ?
This challenge aims to develop a new platform to address the risks of insertional mutagenesis / oncogenesis.
company announces the launch of the Gibson Assembly Site-Directed Mutagenesis Kit which allows researchers to efficiently and accurately perform site-directed mutagenesis on DNA fragments.
coli / Bacillus), Yeast Expression Systems (P pastoris / S cerevisiae), Baculovirus-insect Cell Expression Systems, Mammalian Expression Systems (CHO / 293)), Membrane Protein (Custom Membrane Protein Production, Cell Line Development and Membrane Preparation, Custom Lipoparticle Containing Membrane Protein, Lipid-based Protein Immobilization), PEGylation Services, Directed Evolution, Protein Engineering, Mutagenesis Services (Site-Directed Mutagenesis, Site-Saturation Mutagenesis, Controlled Randomization Service), Protein Microarray , Custom cDNA clone etc.
DNA repair, mutagenesis and other responses to DNA damage; a subject collection from Cold Spring Harbor Perspectives in Biology.
The drug combination was shown to work by lethal mutagenesis that could obliterate HIV by causing the virus to mutate to a point where it was no longer infectious.
Efforts are underway to verify the location of the second site by site-directed mutagenesis and the substituted cysteine accessibility method (SCAM).
We now know the 93 genes more than half of which are funneling into three nodes that go down the mutagenesis pathway," said Rosenberg, professor of molecular and human genetics at Baylor College of Medicine and 2009 winner of the National Institutes of Health Director's Pioneer Award.
Also, Dr Macleod said: "Not only will this partnership allow students, faculty and staff from CNA-Q and QU to share research and training opportunities, they will also be able to fully utilise the newest of CNA-Q's purpose built facilities in the Radiation Genetics and Chemical Mutagenesis laboratory.
However, GM makes possible genetic changes, including between animals and plants, which would be highly unlikely or never occur using mutagenesis or other conventional techniques.
399) used cell-based reporter assays, in silica iigand-PXR docking studies, and site-direct mutagenesis to study the interaction between BPA and PXR, and the influence of BPA and its analogs on the regulation of PXR target genes in human LS180 cells.
They cover mutagenesis in various microbial backgrounds, polymerase chain reaction mutagenesis, protein evolution mutagenesis, protein structure and function mutagenesis, random mutagenesis, and mutator bacterial strain mutagenesis.
Emphasis was directed at chromosome 15, the target chromosome in the mutagenesis scheme.