myeloblast


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Related to myeloblast: myeloblastic leukemia

my·e·lo·blast

 (mī′ə-lə-blăst′)
n.
An immature cell of the bone marrow that is the precursor of a myelocyte.

my′e·lo·blas′tic adj.

myeloblast

(ˈmaɪələʊˌblɑːst)
n
(Pathology) a cell that gives rise to a granulocyte, normally occurring in the bone marrow but detected in the blood in certain diseases, esp leukaemia
myeloblastic adj
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.myeloblast - a precursor of leukocytes that normally occurs only in bone marrow
leucocyte, leukocyte, WBC, white blood cell, white blood corpuscle, white cell, white corpuscle - blood cells that engulf and digest bacteria and fungi; an important part of the body's defense system
Translations

my·e·lo·blast

n. mieloblasto, una célula no madura en la serie granulocítica, generalmente presente en la médula ósea.
References in periodicals archive ?
NRP-1 expression was directly correlated with myeloblast percentage in the bone marrow of patients with AML, suggesting that NRP-1 correlates with tumor load.
Pluripotential stem cell Myeloid Progenitors Myeloblast Monoblasts Marrow pool Mitotic Promelocytes Promonocytes precursors Myelocytes Post-mitotic Metamyelocytes bands Blood and Neutrophils, Monocytes tissue eosinophils and function basophils Innate Macrophage immunologic function Progenitors Megakaryocyte Erythroid Lymphoid Marrow pool Mitotic Maturing Normoblasts Pre-B precursors megakaryocytes Post-mitotic Reticulocytes B lymphoblast Blood and Platelets Erythrocytes B tissue lymphocytes function and plasma cells Haemostasis Oxygen Adaptive transport immunologic function Progenitors Marrow pool Mitotic Pro-T precursors Post-mitotic Lymphoblast Blood and T-lymphocytes tissue and NK cells function Fig.
Human acute myelogenous leukemia (AML) often arises from neoplastic transformation of pluripotent stem cells, resulting in cell immaturation at the recognizable levels of myeloblast or promyelocyte stages.
During this period, the bone marrow myeloblast count increases to 5 to 30%.
Immature granulocytes are defined as the collection of maturing granulocytic myeloid cells that have differentiated beyond the myeloblast stage, but have not yet reached the stages of band form neutrophils, eosinophils, or basophils.
AML is characterized by a higher rate of abnormal hematopoietic stem cells in bone marrow than in MDS, and inefficient production of blood cells and peripheral organ failure due to migrating myeloblasts.
Myeloid sarcoma, also known as chloroma, extramedullary myeloid tumor or granulocytic sarcoma, is an extramedullary tumor mass consisting of immature myeloid cells and/or myeloblasts.
Per WHO classification, erythroleukemia is defined as [greater than or equal to] 20% myeloblasts in the nonerythroid cell population with [greater than or equal to] 50% erythroid precursors in the bone marrow.
Myeloid sarcoma is defined as a tumor mass of myeloblasts or immature myeloid cells involving an extramedullary anatomic site (1) and can occur in 3% to 8% of patients with acute myeloid leukemia (AML).
When considered primary internal malignancies of these patients, 6 patients were diagnosed with gastrointestinal malignancy, 4--with lung cancer, 4--with breast cancer, 3--with malignant melanoma, 1--with Ewing's sarcoma, 1--with acute myeloblasts leukemia and 1 patient was diagnosed with prostatic cancer.
Of 44 children with Nl, 57% (n=25) had acute lymphoblastic leukemia (ALL), 18% (n=8) had non-Hodgkins lymphoma, 9% (n=4) had acute myeloblasts leukemia (AML), 7% (n=3) had neuroblastoma, and 9% (n=4) had other solid tumors.