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A semisynthetic penicillin, C21H22N2O5S, that is resistant to penicillinase, used in the form of its sodium salt primarily to treat infections caused by penicillinase-producing staphylococcus bacteria.

[naf- (shortening and alteration of naphthalene) + (peni)cillin.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nafcillin - a penicillinase-resistant form of penicillin (trade name Nafcil) used (usually in the form of its sodium salt) to treat infections caused by penicillin-resistant strains of staphylococci
penicillinase-resistant antibiotic - a form of penicillin that is not rendered inactive by penicillinase


n nafcilina
References in periodicals archive ?
Zhang, Preparation and Application of Core-Shell Structural Carbon Nanotubes-Molecularly Imprinted Composite Material for Determination of Nafcillin in Egg Samples, Chinese J.
aureus is best treated with a semisynthetic penicillin, nafcillin, oxacillin, flucloxacillin or cephalosporin (Cefazolin).
The Mayo Clinic lists the following as commonly prescribed antibiotics to treat staph infection: certain cephalosporins, nafcillin or related antibiotics, sulfa drugs or vancomycin.
The major intramammary antimicrobial treatments that have been used with different success rates to control bovine mastitis include beta-lactams such as natural G penicillins (sodium, potassium, procaine and benzathine), synthetic ones such as ampicillin, amoxicillin and anti-staphylococcus drugs (cloxacillin, oxacillin, nafcillin, meticillin); cephalosporins (Cefapirin, cefalonium, cephalothin, cefoperazone, ceftiofur, cefquinome); aminoglycosides such as dihydrostreptomycin, gentamicin and neomycin; aminocoumarins (novobiocin); fluoroquinolones (norfloxacin); tetracyclines (oxytetracycline); macrolides (erythromycin); lincosamides such as lincomycin and pirlimycin; chloramphenicol, among others.
She received an 8-week course of Nafcillin and Rifampin, as well as two weeks of Gentamicin, with subsequent improvement.
For methicillin-sensitive strains, penicillinase-resistant penicillins like flucloxacillin, nafcillin, or oxacillin are the drugs of choice (3,7).
Comparative evaluation of oral levofloxacin and parenteral nafcillin in the treatment of experimental methicillin- susceptible Staphylococcus aureus osteomyelitis in rabbits.
com)-- Bioo Scientific's MaxSignal[R] Beta-Lactam ELISA Test Kit has been validated for the screening of a wide range of beta-lactam antibiotics including ampicillin, penicillin G, amoxicillin, azlocillin, piperacillin, nafcillin, cloxacillin, oxacillin, cefoperazone, ceftiofur and other beta-lactams in a number of food matrices.
Common antibiotics used are Nafcillin, Clindamycin, 1st generation Cephalosporin or Vancomycin (6).
The most commonly used antibiotics included oxacillin, nafcillin, cefathiamidine and vancomycin had the highest resistance to S.
Patients with STSS typically received intravenous clindamycin 600 mg every 8 h plus oxacillin or nafcillin 2000 mg every 4 h.
14) Moreover upregulation of PVL toxin observed with nafcillin (15) could also result with flucloxacillin when used for treating MSSA.