nalidixic acid


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na·li·dix·ic acid

 (nā′lĭ-dĭk′sĭk)
n.
An antibacterial drug, C12H12N2O3, used to treat urinary tract infections caused by gram-negative bacteria.

[Blend of naphthyridine (naphth(alene) + (p)yridine) and carboxylic acid, two of its constituents.]

nalidixic acid

(ˌnælɪˈdɪksɪk)
n
a synthetic antibiotic used to treat infections of the urinary tract. Formula: C12H12N2O3
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nalidixic acid - antibacterial agent used especially to treat genitourinary infections
antibacterial, antibacterial drug, bactericide - any drug that destroys bacteria or inhibits their growth
Translations

nalidixic acid

n ácido nalidíxico
References in periodicals archive ?
Ampicillin resistance dropped from 35% to 30%, nitrofurantoin resistance dropped from 93% to 92%, and nalidixic acid resistance remained steady at 97%.
Todd-Hewitt broth supplemented with either colistin (10 [mu]g/mL) and nalidixic acid (15 [mu]g/mL) or with gentamicin (8 [mu]g/mL) and nalidixic acid (15 [mu]g/mL) may be used; appropriate commercially available options include Lim or SBM broth.
Ciprofloxacin, Norfloxacin, Linezolid, Meropenem, Nalidixic Acid, Nitrofurantoin, Tobramycin and Cefazolin.
India, Pakistan, Bangladesh) often are resistant to the quinolone nalidixic acid or are multidrug resistant (i.
However, the direct antimicrobial susceptibility plates revealed dual zones of inhibition around nalidixic acid.
Merseyside, UK): Ampicillin (10ug), Chloramphenicol (30ug), Cefuroxime (30ug), Ceftriaxone (30ug), Gentamycin (30ug), Cotrimoxazole (25ug), Nalidixic Acid (30ug), Ciprofloxacin (5ug) and Augmentin (30ug).
Over a decade ago, results of active surveillance studies showed that, in most endemic countries, especially in Asia and sub-Saharan Africa, there was an emergence of multidrug resistance to different antimicrobials, including ampicillin, co-trimoxazole, and nalidixic acid (9).
All cry4 positive Bt isolates and positive controls of cry4 gene IPS78 and HD500 were found resistant to ampicillin, amoxicillin and bacitracin and were sensitive to chloramphenicol, erythromycin, kanamycin, neomycin, nalidixic acid, oxytetracyclin, polymixin, streptomycin, tetracyclin and vancomycin.
The antimicrobial susceptibility tests included the following drugs: amikacin (an aminoglycoside), cephalexin, cefuroxime and cephotaxime (1st, 2nd and 3rd generation cephalosporins, respectively), norfloxacin, ciprofloxacin and nalidixic acid (fluoroquinolines), nitrofurantoin, ampicillin, and trimethoprim-sulfamethoxazole (TMP/SMX).
cholerae isolates were sensitive to tetracycline, gentamycin and azithromycin but resistance for ampicillin, co-trimoxazole, nalidixic acid, and furazolidone.
group B streptococcus infection was detected in 21 patients by using the cheaper, more rapid colistin and nalidixic acid agar (CNA) culture system.
Based on these findings, MSF emphasized treatment of dysentery with a complete course of nalidixic acid and improvement of basic sanitation and hygiene.