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The absence of diabetic thick skin and necrobiosis lipoidica diabeticorum (NLD) in the present study when compared to other studies,2,8,23 (Table 5) is mainly due to short duration of DM in the majority of the patients.
Some of the cutaneous markers of diabetes mellitus like necrobiosis lipoidica diabeticorum (NLD is a degenerative disease of connective tissue seen in almost 50% of diabetic patients.
In addition, sporadic hepatic necrobiosis observed in samples of several AD rabbits was the most severe finding and indicated gradual, less fulminant development of IRI compared with CG and PGE1 animals.
Differential diagnoses for perineal nodular induration Differential diagnosis Histolopathological features Ischemic fasciitis (13-15) Outer fringe of mitotically active fibroblasts and occasional ganglion-like cells and small vessels surrounding a central zone of necrobiosis Cellular angofibrom (*16) Uniformly moderately cellular with plump, bland spindle cells, hyalinized round, thick and walled vessels may contain adipose tissue Angiomyofibroblastoma-like tumour Alternating hypercellular and of the male genital tract (*17) hypocellular areas with clusters of rounded, epithelioid cells around numerous small vessels Mammary type fibroblastoma (*18) Well-circumscribed, more cellular, and lacks a central zone pattern.
In the model group, there was serious large-area necrobiosis in the ventricular membrane and subendocardial with fibroblastic proliferation and presence of inflammatory cells infiltration.
Pigmentation and dermatosderosis may be mimicked by disorders such as dermatitis, myxoedema, necrobiosis diabeticorum, conditions with increased intra-abdominal pressure, i.
On the contrary it's easy to determine tissue not subjected to necrobiosis.
Histopathologic evaluation also included evaluation for an interstitial pattern of the lymphohistiocytic infiltrate (consistent with "incomplete" granuloma annulare) or a palisading pattern with central necrobiosis (granuloma annulare, common variant), increased dermal mucin deposition (highlighted by colloidal iron stain), presence of multinucleated giant cells, elastophagocytosis, and eosinophils.
The neoplasm, which had apoptotic bodies and necrobiosis, also invaded the full thickness of the skin, and the epidermis was very thin.
Necrobiosis lipoidica diabeticorum (NLD) is a disorder involving subcutaneous collagen degeneration that results in thickening of blood vessel walls, fat deposition, and the formation of granulomas.
Era similar a endosepsis (17), a necrobiosis o a sapremia puerperal cuyo significado original era "mero o simple envenenamiento por productos quimicos de la putrefaccion" (20).
Medicina: acondroplasia, acromatopsia, diploneural, necrobiosis, paracentesis, simbalofono.