Biopharmaceutical corporation Prometic Life Sciences Inc (TSX:PLI) (OTCQX:PFSCF) revealed on Thursday that it has passed the US Food and Drug Administration's (FDA) orphan drug designation status for its Inter-Alpha-Inhibitor-Proteins (IaIp) for the treatment of necrotizing enterocolitis
8226; Disseminating credible and timely information about Necrotizing Enterocolitis
(NEC) to parents whose infants are most at risk for developing NEC
Impact of gestational age on the clinical presentations and surgical outcome of necrotizing enterocolitis
KEY WORDS: Newborn, Neonatal Necrotizing Enterocolitis
, Abdominal Ultrasound.
In Norway, a consensus-based protocol recommending prophylactic probiotic supplementation for preterm infants at highest risk for necrotizing enterocolitis
(gestational age <28 weeks, birthweight <1,000 g) was introduced in 2014.
Dietary supplements thought to have probiotic effects have been reported to reduce the incidence of necrotizing enterocolitis
and all-cause mortality in preterm infants (4), although there are concerns that the safety of the products has not been adequately documented (5).
Put onto special breathing apparatus, he made it through his first few days only to contract necrotizing enterocolitis
, or dying tissue in his bowel.
The gestational age, mode of delivery (cesarean/vaginal), birth weight, height and head circumference, gender, if resuscitation was performed at birth, if steroid was given to the mother before delivery, the type and amount of surfactant administered, if a second dose of surfactant was administered, the time of respiratory support given, hospitalization time, presence of complications including bronchopulmonary dysplasia (BPD) and necrotizing enterocolitis
and blood gases values measured at 6-hour intervals in the first 24 hours in the babies in the study group were recorded.
Oral probiotics prevent necrotizing enterocolitis
in very low birth weight neonates.
This can lead to an array of problems, from trouble breathing, to heart defects and low blood pressure, anemia, jaundice and necrotizing enterocolitis
(where portions of the infant's bowel die).
It becomes clear that the child has developed a major problem in his or her tummy, and an X-Ray will usually confirm the diagnosis of necrotizing enterocolitis
, or NEC, in which the intestinal tissue is dying.
Cronobacter sakazakii is an emerging opportunistic pathogen of the family Enterobacteriaceae responsible for outbreaks of neonatal meningitis and necrotizing enterocolitis
in the immunocompromised.