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neostigmine

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ne·o·stig·mine  (n-stgmn, -mn)
n.
Either of two related white crystalline compounds, C12H19BrN2O2 or C13H22N2O6S, that opposes the action of acetylcholinesterase and is used in the treatment of glaucoma, myasthenia gravis, and various postoperative conditions.

ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.neostigmine - a cholinergic drug (trade name Prostigmin) used to treat some ophthalmic conditions and to treat myasthenia gravis
anticholinesterase - a medicine that inhibits cholinesterase by combining with it and so has a cholinergic effect


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Results from a pooled analysis of Phase II and III clinical trial data showed that sugammadex reversed the effects of shallow rocuronium-induced muscle relaxation during general anesthesia in just under two minutes (median time to reversal), over nine times faster than neostigmine, and almost 20 times faster than placebo.
With one exception, which show an unexplained potentiation of neostigmine stimulated colon activity, all other studies result in effects, indicating a substantial spasmolytic effect of PO of the smooth muscles of the gastrointestinal tract.
 
 
 
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