This damages the myelin and disrupts messages travelling along nerve fibres
- they can slow down, become distorted, pass from one nerve fibre
to another, or not get through at all.
The research debunks the theory that the nervous system should have mainly very short nerve fibre
connections between nerve cells, or neurons, to function.
If successful, it will open the door to treating conditions including spinal injuries, the most severe strokes and blindness and deafness caused by nerve fibre
The loss of myelin in the brain prevents nerve fibres
from sending signals properly and will eventually lead to the loss of the nerve fibre
The study found long nerve fibre
connections are just as vital as short ones, rebuffing the theory the nervous system should have mainly very short nerve fibre
connections between nerve cells to function.
damage is typically assessed through invasive tests, including nerve and tissue biopsies.
According to the research team, each individual nerve fibre
was responsible for touch signals from roughly a square centimetre of skin.
Together with ONFs, they make bundles of nerve fibres
that run from the nasal mucosa to the olfactory bulb, where the sense of smell is located.
When the nerve fibres
that carry smell become damaged, they are replaced by new nerve fibres
which re-enter the olfactory bulbs, the researchers explained in their study.
In particular, they investigated changes in the nerves and tissues around the arthritic joint, by using specific markers to label the different types of nerve fibres
and allow them to be visualized with a fluorescence microscope.
progress from the receptors through tiny holes in the roof of the nasal cavity and come together to form two structures called the olfactory bulbs.
The US team showed that regenerating nerve fibres
can reform connections after being guided to the right targets.