nerve growth factor


Also found in: Thesaurus, Medical, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.

nerve growth factor

n. Abbr. NGF
A protein that stimulates the growth of sympathetic and sensory nerve cells.

nerve growth factor

n
1. (Physiology) a polypeptide produced by neurones and their supporting tissues as well as some other tissues that stimulate the growth of neurones
2. (Physiology) any of various related polypeptides that promote the growth of neurones
Abbreviation: NGF

nerve′ growth` fac`tor



n.
a protein that promotes the growth, organization, and maintenance of sympathetic and some sensory nerve cells. Abbr.: NGF
[1965–70]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nerve growth factor - a protein that is involved in the growth of peripheral nerve cells
growth factor - a protein that is involved in cell differentiation and growth
References in periodicals archive ?
rhNGF, the Recombinant Human Nerve Growth Factor developed by Dompe, is identical to the protein that is naturally produced by the body and promotes the development and survival of nerve cells, including those of the retina.
Bartus and his associates at Ceregene (where he served as chief scientific officer for more than 10 years) developed a viral gene therapy vector bioengineered to express only the gene for human nerve growth factor (AAV2-NGF, or CERE-110).
Key words: Brain derived nerve growth factor, cardiovascular disease, atherosclerosis, dyslipidemia, diabetes mellitus
Over the past year, the Food and Drug Administration has put on clinical hold nearly all programs for nerve growth factor inhibitor (anti-NGF) development, particularly those related to treating knee pain in osteoarthritis.
With chlorpyrifos addition during mid-differentiation (four days after nerve growth factor pretreatment), ChAT was unaffected, but TH was increased slightly.
Studies of the neurotropic desmoplastic variant of melanoma have correlated the overexpression of the 75-kD neurotrophin receptor (p75NTR), a cell-surface molecule, and its ligand, nerve growth factor, with the propensity for perineural invasion.
Engineered chemicals known as nerve growth factor seem to slow the debilitating illness.
In their experiment, the researchers took skin samples from the patients and genetically modified them to produce extra nerve growth factor, a protein that prevents cell death and stimulates cell function.
The company has exclusive rights to related technology that is being used in an ongoing Phase I clinical study at the UCSD, delivering nerve growth factor to Alzheimer's disease patients by gene therapy.
PC12 cells can be induced to differentiate into a neuron-like cell and project neurite extensions from the cell body within 24 hours of stimulation with Nerve Growth Factor (NGF).
Instead they repair and rebuild themselves using proteins called Nerve Growth Factor (NGF).