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Related to neuraminidase: sialic acid, Neuraminidase inhibitor


 (no͝or′ə-mĭn′ĭ-dās′, -dāz′, nyo͝or′-)
A hydrolytic enzyme that removes sialic acid from glycoproteins and is found in many cells and viruses. It occurs on the surface of influenza viruses and enables the release of newly replicated viruses from infected cells.

[neuramin(ic acid) (neur(o)- + amin(e)) + -id(e) + -ase.]


(Biochemistry) any of various enzymes, found esp in viruses, that catalyse the breakdown of glucosides containing neuraminic acid, an amino sugar
[C20: from neuramin(ic acid) (from neuro- + amine + -ic) + -ide + -ase]
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References in periodicals archive ?
Salmonella infection elevated neuraminidase activity in the small intestine, which in turn accelerated the molecular aging and turnover of IAP, resulting in IAP deficiency in the colon.
The license agreement with Mount Sinai will provide InDevR with a unique set of anti-neuraminidase monoclonal antibodies for rapid, subtype specific quantification of neuraminidase in the multiplexed VaxArray system.
Neuraminidase (NA) inhibitors (NAIs) are the only drugs available for treating influenza B virus infections, but NA mutations that emerge during treatment or due to natural variance can diminish the usefulness of NAIs.
Peramivir is an intravenous (IV) viral neuraminidase inhibitor that is used for the treatment of influenza in patients who are over 18 and have exhibited symptoms for no more than two days.
SAN DIEGO--The neuraminidase inhibitor peramivir inhibited about 99% of seasonal influenza A and B viruses circulating globally during the 2013-2014 and 2014-2015 influenza seasons, a large analysis demonstrated.
BioCryst Pharmaceuticals became the first company in the US with approval to sell an intravenous neuraminidase inhibitor as an influenza treatment.
The pharmaceutical oseltamivir (Tamiflu) can stop the virus because it is a neuraminidase inhibitor.
Biochemical Analysis of Samples: The sample were processed and analyzed for the estimation of Glutathione (GSH) Catalases Super Oxide Dismutase (SOD) Malondialdehyde (MDA) Sialic acid and Neuraminidase by the spectrophotometric method.
2]-transferrin in CSF is desialylated because of the presence of neuraminidase in the central nervous system.
The ubiquitous H1N1 and H3N2 flu strains, for example, use the protein hemagglutinin (H) to bind to matching sialic acid receptors on the surface of a cell before penetrating it, and then use the enzyme neuraminidase (N) to cleave or split these sialic acids when viral particles are ready to exit and spread the infection.
Hemagglutinin and neuraminidase are two key proteins displayed on the surface of the virus particle; they are the H and N used in virus strain names like H1N1.