nevirapine


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ne·vir·a·pine

 (nə-vîr′ə-pēn′, -pĭn)
n.
An antiviral drug, C15H14N4O, that is a non-nucleoside reverse transcriptase inhibitor and is used in combination with other drugs for the treatment of HIV infection.

[ne- (probably shortening of non-nucleoside) + vir(us) + alteration of (diaz)epine.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nevirapine - a non-nucleoside reverse transcriptase inhibitor (trade name Viramune) used to treat AIDS and HIV
NNRTI, non-nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs
Translations

nevirapine

n nevirapina
References in periodicals archive ?
launch of Nevirapine Extended-release Tablets, 100 mg, the generic version of Boehringer Ingelheim's Viramune XR[sup.
1 Zidovudine 300 mg + Lamivudine 150mg + Nevirapine 200 mg.
The link between systemic hypersensitivity reactions and nevirapine has been well documented.
The political and practical difficulties of introducing nevirapine to Africa where HIV infection rates are high round out the last several chapters.
Women in the maternal-antiretroviral group, but not their infants, continued taking zidovudine, lamivudine and nevirapine, although after February 2005 other drugs were substituted for nevirapine in this group because of toxicity concerns.
Adding the drug nevirapine to the regimen given to newborns of women diagnosed with HIV shortly before or during labor halves the newborns' risk of contracting the virus, according to findings by a National Institutes of Health research network.
Use of nevirapine with co-trimoxazole prophylaxis in HIV-exposed, uninfected (HIV-EU) infants until 6 months of age in Zimbabwe and Uganda was safe with no immediate or long-term adverse effects, researchers on behalf of the HIV Prevention Trials Network (HPTN) 046 protocol trial report in the advance online edition of AIDS.
Recent findings from five randomised trials in the US, Ethiopia, India, Uganda and Malawi show that extended use of nevirapine or zidovudine plus nevirapine in breastfeeding infants can reduce the risks of HIV transmission through breastmilk by 71%.
Washington, Mar 3 (ANI): In a new study, scientists found that giving breastfeeding infants of HIV-infected mothers a daily dose of the antiretroviral drug nevirapine for six months halved the risk of HIV transmission to the infants at age 6 months compared with giving infants the drug daily for six weeks.
Several regimens have been tested for prevention of parent-to-child transmission (PPTCT), including nevirapine (NVP) given as a single dose to the mother at the time of delivery followed by a single dose to the infant within 72 h (Sd-NVP) (2).
As I regaled him with the evidence that I had collected, he asked me if I had been following the scandalous revelations about the HIV-nevirapine study conducted in Africa, a highly funded, highly lauded National Institutes of Health (NIH) project testing the use of the anti-HIV drug nevirapine to prevent the transmission of HIV from infected pregnant women to their babies.
NNRTIs such as efavirenz or nevirapine have been associated with hepatotoxicity mainly by two mechanisms.