chronic granulomatous disease

(redirected from nitroblue tetrazolium test)
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Related to nitroblue tetrazolium test: chronic granulomatous disease

chron·ic gran·u·lom·a·tous dis·ease

n. encefalomielitis, enfermedad que puede ser fatal causada por inmuno deficiencia y grave deficiencia de leucocitos.
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To study the serum alpha-1 antitrypsin levels in patients of CRF on long-term dialysis at different intervals (before, immediately after, and 8 hours after dialysis) and to appreciate and establish the extent of neutrophil activation in CRF patients by the Nitroblue Tetrazolium Test (NBT test).
Laboratory evaluation for neutrophil's oxidative burst was performed and diagnosis of chronic granulomatous disease (CGD) was confirmed by both negative Nitroblue tetrazolium test (NBT) and lack of dihydrorhodamine (DHR) fluorescence following neutrophil stimulation against phorbol myristate acetate (PMA).
Immunological profile was as follows: Nitroblue tetrazolium test was 99%, which was interpreted as normal.