nitrogen mustard


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nitrogen mustard

n.
One of a group of toxic organic compounds that are structurally similar to mustard gas but contain nitrogen instead of sulfur, used primarily as chemotherapeutic agents.

nitrogen mustard

n
(Elements & Compounds) any of a class of organic compounds resembling mustard gas in their molecular structure. General formula: RN(CH2CH2Cl)2, where R is an organic group: important in the treatment of cancer
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Noun1.nitrogen mustard - a toxic compound resembling mustard gas in structure; important in cancer treatment
chemical compound, compound - (chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight
References in periodicals archive ?
People have been trying to write the epitaph for chemotherapy virtually since nitrogen mustard was approved in 1949.
Nitrogen mustard was found to be less toxic and the chemical agent became a new weapon in the fight against cancer still used today.
As reported in this month's issue, a research group exposed cultures of immature neurons known as granule cells and the more developed and more abundant astrocytes to sublethal doses of two well-characterized alkylating genotoxicants: methylazoxymethanol (MAM), a highly toxic compound synthesized from the poison found in plants called cycads, and nitrogen mustard (HN2), a chemotherapeutic agent.
Chemotherapy drugs called alkylating agents, which include cytoxan and nitrogen mustard, carry the highest risk of infertility.
Recent studies reaffirm the effectiveness of two such treatments: anthralin and nitrogen mustard, said Dr.
Mycosis fungoides: management with topical nitrogen mustard.