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nitrogen mustard

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
nitrogen mustard
n
(Chemistry / Elements & Compounds) any of a class of organic compounds resembling mustard gas in their molecular structure. General formula: RN(CH2CH2Cl)2, where R is an organic group: important in the treatment of cancer
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.nitrogen mustard - a toxic compound resembling mustard gas in structure; important in cancer treatment
chemical compound, compound - (chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight


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Nitrogen mustard has also demonstrated activity in other T-cell proliferating diseases such as psoriasis and alopecia areata and has a rich history of use in dermatology dating back to the 1950s.
Chinese anti-tumor drugs can be divided into nine categories: Alkylation Agents, such as nitrogen mustards, ethylene-imines, methanesulfonates, polyatomic alcohols and SarCNU; Anti-metabolite drugs, such as pyrimidine antimetabolites, purine antimetabolites and antifolates; Antibiotics; Plant anti-tumor drugs; Hormone anti-tumor drugs; Platinum metallic anti-tumor drugs; Others; Aided anti-tumor Drugs and immunomodulators.
Chemotherapy for the treatment of cancer began in the 1940s with the use of nitrogen mustard.
 
 
 
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