nucleophilic


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nucleophilic

(ˌnjuːklɪəʊˈfɪlɪk)
adj
(Chemistry) chem having or involving an affinity for positive charge. Nucleophilic reagents (nucleophiles) are molecules, atoms, and ions that behave as electron donors. Compare electrophilic
Translations
nucléophile
References in periodicals archive ?
Among their topics are addressing the challenges of stand-alone multi-core simulations in molecular dynamics, an analytical solution of the pantograph equation with incommensurate delay, the mechanism of nucleophilic substitution reactions of 4-(4'-nitro) phenylnitrobenzofurazan ether with aniline in acetonitrile, computational methods in pre-formulation study for pharmaceutical solid dosage forms of therapeutic proteins, and elemental two-dimensional materials beyond graphene.
Thus, depending on the nature of reactive group/s they constitute a triazinyl ring or vinyl sulphone group, which react with the hydroxyl group of cellulose undergoing nucleophilic substitution reactions.
In order to identify pathways associated with protein reactivity, the same variance-filtered dataset was filtered based on two-group comparisons (t-tests, Toxtree binding class "no binding" non-sensitizers (81 samples) versus "Michael acceptor" sensitizers (MA, 63 samples), "no binding" versus "Schiff base formation" (SB, 29 samples), "no binding" versus combined "bi-molecular nucleophilic substitution/nucleophilic aromatic substitution" (SN, 25 samples).
acylation) often occurs on o-position, and nucleophilic substitution reaction (e.
It was found that oxirane ring undergoes nucleophilic attack by the primary amine groups of chitosan and the degree of crosslinking increased with increase in curing time, curing temperature and concentration of chitosan.
Another mode of action is possibly through the interaction of the DNA's nucleophilic sites with the bioactive compounds present in the extract hence the mutagen could no longer bind to these sites [13].
It was not until 1979 that a glycosyl donor was designed based on the nucleophilic attack of 1-hydroxy sugar 1 to an electrophile 2 (Fig.
Metabolism of drugs and actives usually involves two phases; the first phase includes oxidation, reduction and hydrolysis, introducing or exposing nucleophilic groups on the compound.
5 Glutathione is a nucleophilic scavenger of many chemical compounds and there metabolites through enzymatic and chemical mechanisms thus gives protection against oxidative damage which is caused due to reactive oxygen species.
Osterholtz and Pohl proposed a bimolecular nucleophilic displacement reaction consistent with their kinetic data, as depicted in Figure 9 for base catalysis of alkoxysilane hydrolysis, involving a pentacoordinate intermediate, and two different transition states, T.
The structure and biochemical results show that priming involves autocleavage of the membrane penetration protein and suggest that Lys84 and Glu76 may facilitate this autocleavage in a nucleophilic attack.
In the first months of a Merlot trial in Medoc, France, ellagitannins were extracted at a rate faster than the rate of the condensation reactions between ellagitannins and other nucleophilic wine constituents (catechin, epicatechin and ethanol).