Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia.


 (no͞o′klē-ō-prō′tēn′, -prō′tē-ĭn, nyo͞o′-)
Any of a group of complexes composed of protein and nucleic acid and found in the nuclei and cytoplasm of all living cells, as in chromatin and ribosomes, and in viruses.


(Biochemistry) a compound within a cell nucleus that consists of a protein bound to a nucleic acid


(ˌnu kli oʊˈproʊ tin, -ti ɪn, ˌnyu-)

any of the class of conjugated proteins occurring in cells and consisting of a protein combined with a nucleic acid, essential for cell division and reproduction.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nucleoprotein - any of several substances found in the nuclei of all living cells; consists of a protein bound to a nucleic acid
protein - any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
References in periodicals archive ?
qRT-PCR results for EBOV nucleoprotein from guinea pig oral swab and blood samples collected, by number of days postinfection * Sample type, blood or oral/bloodt Dose, ID Virus type [TCID.
Previous attempts to target nucleoprotein for protection were not effective.
Nonhomologous recombination between the hemagglutanin gene and the nucleoprotein gene of an influenza virus.
The absence of fast green staining in sperm after DNA extraction by TCA and their retention of a high concentration of arginine reaction products suggests that a conversion from a primarily histone type of basic nucleoprotein to a more arginine-rich, protamine-like protein accompanies spermiogenesis in these spiders.
However, eukaryotic cells contain an additional level of information superimposed on the DNA double helix in the form of a complex nucleoprotein entity generically termed "chromatin.
Sections from routinely processed paraffin-embedded tissue were examined immunohistochemically, as previously described for measles, using a 1:50 dilution of monoclonal anti-measles nucleoprotein (Light Diagnostics, Temecula, Calif), the EnVision system (Dako, Glostrup, Denmark), and fast red as the chromogen.
In 1993, the Merck researchers showed that a plasmid containing the gene for the internal nucleoprotein (NP) of influenza evoked an immune response to a different strain of the influenza virus in mice.
Structural disorder within the Sendai virus nucleoprotein and phosphoprotein
Of these contigs, 3 (129-354 nt) were genetically close to filovirus, corresponding to the nucleoprotein gene of LLOV (74% nt identity), the viral protein 35 gene of Sudan Ebola virus (69% nt identity), and the L gene of Tai Forest Ebola virus (72% nt identity) (online Technical Appendix Table 1, http://www.
Because of its vital function, the nucleoprotein is highly conserved, making it a good potential target for antiviral drugs.
DNA in higher organisms is organized in a nucleoprotein complex called chromatin.
Two chapters are devoted to the general functions of the nucleoprotein in transcription and replication and to a detailed overview of its structural properties.