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nucleoside

   Also found in: Medical, Encyclopedia, Wikipedia 0.03 sec.
nu·cle·o·side  (nkl--sd, ny-)
n.
Any of various compounds consisting of a sugar, usually ribose or deoxyribose, and a purine or pyrimidine base, especially a compound obtained by hydrolysis of a nucleic acid, such as adenosine or guanine.

nucleoside [ˈnjuːklɪəˌsaɪd]
n
(Life Sciences & Allied Applications / Biochemistry) Biochem a compound containing a purine or pyrimidine base linked to a sugar (usually ribose or deoxyribose)
[from nucleo- + -ose2 + -ide]

nucleoside  (nkl--sd)
Any of various compounds consisting of a sugar, usually ribose or deoxyribose, and a nitrogen base (a purine or pyrimidine). Nucleosides are constituents of the nucleotides of nucleic acids. Adenosine and thymidine are nucleosides.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.nucleoside - a glycoside formed by partial hydrolysis of a nucleic acid
adenosine - (biochemistry) a nucleoside that is a structural component of nucleic acids; it is present in all living cells in a combined form as a constituent of DNA and RNA and ADP and ATP and AMP
glycoside - a group of compounds derived from monosaccharides
inosine - a nucleoside that is formed by the deamination of adenosine; used in kidney transplantation to provide a temporary source of sugar
deoxyadenosine - a nucleoside component of DNA; composed of adenosine and deoxyribose
cytidine, deoxycytidine - a nucleoside component of DNA; composed of cytosine and deoxyribose
deoxyguanosine, guanosine - a nucleoside component of DNA; composed of guanine and deoxyribose
deoxythymidine, thymidine - a nucleoside component of DNA; composed of thymine and deoxyribose


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Topics include the history of the discovery of modified nucleosides in DNA and RNA and corresponding modification-editing enzymes; the mechanistic and functional aspects of DNA modification and editing; problems related to DNA/RNA repair and base editing; the interplay between DNA and RNA modifications and the emergence of DNA; complementary aspects of RNA modification enzymes and their cellular implications; and incorporating modified nucleosides by in vitro chemical synthesis.
The company also has a comprehensive HCV discovery effort, comprised of a next-generation nucleoside polymerase inhibitor program, including IDX102 and IDX184, which are currently being evaluated in advanced preclinical testing, and HCV non-nucleoside polymerase inhibitor and HCV protease inhibitor programs.
Ed4T, which was developed by Yale University, Kagoshima University and Showa University, is a nucleoside reverse transcriptase inhibitor with enhanced anti-HIV-1 activity.
 
 
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nucleoside monophosphate kinase
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Nucleoside Phosphorylase-2
nucleoside reverse transcriptase inhibitor
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