nude mouse

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nude′ mouse′

a hairless mutant laboratory-bred mouse having an immune system deficiency and able to accept grafts of foreign tissue.
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Noun1.nude mouse - a mouse with a genetic defect that prevents them from growing hair and also prevents them from immunologically rejecting human cells and tissues; widely used in preclinical trials
mouse - any of numerous small rodents typically resembling diminutive rats having pointed snouts and small ears on elongated bodies with slender usually hairless tails
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We conducted a study to examine the viability, host response, and volume retention characteristics of drilled human septal cartilage slurry when injected into an athymic nude mouse model.
Scientists later discover that the nude mouse lacks a functioning thymus, a gland that plays a key role in immune development.
The flux or permeability coefficient, which is the indicator for total absorption of dermal delivery due to the use of nude mouse skin, was the greatest for QM, followed by the glycosides and quercetin.
We found that As-transformed HBECs display highly migratory and invasive potentials, and the nude mouse xenograft tumors resulting from subcutaneous inoculation of As-transformed HBECs were capable of invading into surrounding fat tissues and forming tubelike structures.
Nude mouse tests are now the final, non-human studies required by the National Cancer Institute for determining the effectiveness of potential anticancer agents.
In the second part of the study, we established a nude mouse model to study the relationship between the tumor mass and plasma EBV DNA concentration.