Females in secretory phase of their cycle, having irregular menstrual cycles,
oligomenorrhea, menorrhagia, as well as females on oral contraceptive pills, females with habits of smoking, tobacco chewing, alcohol consumption, and who were diagnosed cases of diabetes mellitus, thyroid disorders, asthma were excluded from the study.
However, Cushing's syndrome is rare in pregnant women because hypercortisolism and hyperandrogenism suppress gonadotropin secretion and leads to amenorrhea or
oligomenorrhea in most cases.
The main presenting symptom of the condition is amenorrhea but due to residual function of ovarian follicles, around half of the women have
oligomenorrhea and spontaneous ovulations (4).
None of the patients had serious systemic side effects, only few had
oligomenorrhea, palpitation and gastric upset.
Sex hormone-binding globulin,
oligomenorrhea, polycystic ovary syndrome, and childhood insulin at age 14 years predict metabolic syndrome and class III obesity at age 24 years.
Oligomenorrhea was defined as the absence of menstruation for 35 days or more and amenorrhea was defined as the absence of menstruation for 3 months or more (1).
Among the menstrual cycle irregularities, most common was
oligomenorrhea, 14 (82.
As per the Rotterdam 2003 criteria, PCOS diagnosis was based on the presence of at least 2 of the following:
oligomenorrhea (more than 45 days between menstrual periods or fewer than 8 menstrual periods per year), hyperandrogenism, clinical hirsutism (acne, hirsutism, androgenic alopecia, acanthosis nigricans) or laboratory findings indicating elevated androgen levels (elevated serum total or free testosterone levels), and the appearance of polycystic ovary on ultrasonography (2-9 mm in diameter, 12 or more follicles and/or increased ovary volume [>10 mL]).
A PCOS diagnosis can be made in adolescent females if there is clinical or laboratory evidence of hyperandrogenism with concomitant persistent
oligomenorrhea.
A total of 248 women with amenorrhea or
oligomenorrhea were screened
The most common bleeding pattern at 3 months after insertion was spotting, and after 6, 9 and 12 months the majority women presented with amenorrhea or
oligomenorrhea.
She had irregular menses in the form of
oligomenorrhea, obesity, acne, hirsutism.
