It's exciting to learn that these different oligomeric
structures bind differently with the human lipid cells," Stahelin said.
Methylene malonate monomers and their oligomeric
crosslinking derivatives have the unique advantage of polymerizing rapidly at ambient temperatures--without the need for ultraviolet light, high temperatures or high solvent loading required by incumbent automotive coating systems.
The extracts were fractionated into anthocyanin, neutral, polymeric and oligomeric
matrix protein (COMP) is a 524-kDa noncollagenous homopentameric protein present in cartilage.
This binding induces essential molecular interactions to break up and thereby solubilizes the oligomeric
form of Abeta.
The approach being taken by Neuropore is to target an underlying pathological process common to these disorders the accumulation of toxic oligomeric
aggregates of misfolded neuronal proteins in cell membranes.
It was recently shown that GCase mutations cause several defects associated with impaired cellular quality control - impaired autophagy, mitochondrial dysfunction and accumulation of oligomeric
alpha-synuclein, a protein strongly involved in sporadic and genetic PD forms.
Polyurethanes are obtained by the reaction of an oligomeric
polyol with a diisocyanate (or polyisocyanate), says Ionescu, and while there are many books on polyurethanes and diisocyanates, this may be the first devoted to oligo-polyols.
In the brains of healthy, nonaltered mice, injections of oligomeric
A-beta, the form thought to be the most dangerous, caused Clq levels to rise.
Elouise Bauskis said: "Grape seed extract, too, contains oligomeric
proanthocyanidins which are highly antioxidant, providing great protection to cells as well as strengthening cell walls.
Skin biopsies showed that the fresolimumab-induced rapid decline in mRSS was accompanied by a sharp drop in skin biomarkers of TGF-beta activity, including expression of the genes thrombospondin-1, cartilage oligomeric
protein, and connective tissue growth factor.
Citation: "Elevated glucose and oligomeric
[beta]-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation," Mohd Waseem Akhtar et al.