Additionally, the state of oligomerisation
is vital as it regulates both signal transduction pathway and overall biological functioning of Acrp30 [34,36,44,45]).
One major pathway in cellular death is apoptosis that involves the release of cytochrome C from mitochondria that in turn binds to a protein known as Apaf-1 (apoptotic protease activating factor 1) and triggers its oligomerisation
and subsequent execution of programmed cell death .
Dunkinb, Ionic liquids: Polar, But Weakly Coordinating Solvents for the First Biphasic Oligomerisation
of Ethene to Higher a-Olefins with Cationic Ni Complexes,Chem.
It contains a nucleotide-binding oligomerisation
domain 2/caspase recruitment domains 15 (NOD2/CARD15) gene mutations, which are strongly associated with the increased risk of developing CD, as confirmed by several research groups [4-9].
Critical role of toll-like receptors and nucleotide oligomerisation
domain in the regulation of health and disease.
Other wellcharacterised families of PRRs in humans are the Toll-like receptors (TLRs), of which there are at least 11 family members, the nucleotide oligomerisation
domain-like receptors (NLRs) consisting of 22 family members, and the abundant cytosolic microbial and viral DNA sensors.
Rhodopsin: structure, signal transduction and oligomerisation