Also found in: Medical, Encyclopedia, Wikipedia.


 (ŏl′ĭ-gō-no͞o′klē-ə-tīd, -nyo͞o′-, ō′lĭ-)
A short polymer of two to twenty nucleotides.


(Biochemistry) a polymer consisting of a small number of nucleotides


(ˌɒl ɪ goʊˈnu kli əˌtaɪd, -ˈnyu-)

a chain of a few nucleotides.
References in periodicals archive ?
The aim of the partnership is to establish a deep alliance to jointly build Asia's largest oligonucleotide drug development and manufacturing facility in China.
Recent technological and other advances, leading to cost effective and rapid synthesis of oligomers, increased government funding and other initiatives, have been driving the global oligonucleotide synthesis market.
Contract notice: Supply, delivery and installation of an oligonucleotide synthesizer, designed to be incorporated in the synthesis of oligonucleotide purification platform and bioimaging of the institute of the university of bordeaux.
Marina Biotech and Girindus Group have entered into a strategic alliance under which Girindus will have exclusive rights to develop, supply and commercialize certain oligonucleotide constructs using Marina's Conformationally Restricted Nucleotide (CRN) chemistry.
The topics include analyzing purity and determining molecular wight by size exclusion high-performance liquid chromatography, the bioanalysis of therapeutic oligonucleotides using hybridization-based immunoassay techniques, analyzing residual solvents by head space gas chromatography, determining structure with nuclear magnetic resonance, determining base composition, and regulatory considerations for developing oligonucleotide therapies.
While traditional methods require eight steps and can take two hours, the Clarity OTX extraction kits isolate oligonucleotide therapeutics and their metabolites in 15 minutes.
Expert commentaries are also included on oligonucleotide microarray hybridization and visible haplotype-tagSNP typing array devices.
Binding of proteins to specific MLL bcr oligonucleotides is indicated by retarded migration in 6% polyacrylamide gels relative to oligonucleotide migration in the absence of proteins.
Within the oligonucleotide sequences, the anti-PDGF-B aptamer sequence (5) is underlined and reporter sequences are in italics.
We next amplified a fragment in rpoB between codons 421 and 701 by using oligonucleotide rpoBF1 (5'gttttcccagtcacgacgttgta-CTGTCCGAAGCCCAA- CAAAACTCTTGG3') and rpoBR1 (5'ttgtgagcggataacaatttcTTCCAAGAATGGAATCAGGGATGCTGC3').
Dalton Pharma Services, a privately owned Canadian pharmaceutical services provider to leading pharmaceutical companies, recently announced the completion of its state-of-art Oligonucleotide Production Suite.
Avecia is the leading GMP oligonucleotide manufacturer, at all scales, from clinical trials to product commercialization.