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 (ŏl′ĭ-gō-no͞o′klē-ə-tīd, -nyo͞o′-, ō′lĭ-)
A short polymer of two to twenty nucleotides.


(Biochemistry) a polymer consisting of a small number of nucleotides


(ˌɒl ɪ goʊˈnu kli əˌtaɪd, -ˈnyu-)

a chain of a few nucleotides.
References in periodicals archive ?
Commonly known as the OLA, the Oligonucleotide Ligation Assay is an analyte specific reagent (ASR) that is centered around the hybridization of a PCR primer with an exact match to a target sequence.
The systems we evaluated included (a) CF oligonucleotide ligation assay (OLA), Ver.
Mutation in the gene coding for coagulation factor V and resistance to activated protein C: detection of the genetic mutation by oligonucleotide ligation assay using a semi-automated system.
It will complement other technologies from the company including the Polymerase Chain Reaction (PCR) and Oligonucleotide Ligation Assay (OLA) chemistries.
Other publications demonstrated that the oligonucleotide ligation assay (36) and single base chain extension (32) could be used for genotyping DNA samples with the microbead approach.
Rapid prenatal diagnosis of sickle cell diseases using oligonucleotide ligation assay coupled with laser-induced capillary fluorescence detection.
Testing the feasibility of DNA typing for human identification by PCR and an oligonucleotide ligation assay.
The oligonucleotide ligation assay (OLA) relies on hybridization with specific oligonucleotide probes that can effectively discriminate between the wild-type and variant sequences.
Minor] mutations from a large number of samples, we utilized PCR followed by oligonucleotide ligation assay (PCR-OLA) (7,8).
These ambiguities can be circumvented by the use of genotyping methods such as allele-specific oligonucleotide hybridization (9), restriction enzyme analysis (ASRA) (10,11), the amplification refractory mutation system (12), oligonucleotide ligation assay (13), heteroduplex analysis (14), or single-strand conformation polymorphism (15).