Methylene chloride: a two-year inhalation toxicity and oncogenicity
study in rats and hamsters.
Heterotopic ossification in the capsule is an adverse effect and must be investigated along with other safety considerations such as oncogenicity
(52) prior to clinical implementation.
Degradation of p53 by human Alphapapillomavirus E6 proteins shows a stronger correlation with phylogeny than oncogenicity
ABL domain mutations leading to the increments in the BCR-ABL oncogenicity
may be detected during the TKI therapy.
Among the topics are oncogenicity
of PAKs and their substrates, natural or synthetic therapeutics that block PAKs, PAK1 in Alzheimer's and Huntington's diseases, and the three-dimensional structure and physiological regulation of PAKs.
When the outcome was stratified by oncogenicity
of HPV type, the association remained statistically significant for having had multiple sex partners.
senior author on the study, added, "This is the first demonstration of using RNA electroporation rather than viral vectors, which have been the method of choice to express IL-4 ectopically, but carry the risks of immunogenicity and oncogenicity
Studies of Inhaled Methyl Tertiary-butyl Ether (MTBE)
of specific HPV variants appears to vary geographically and also with the ethnic origin of the population studied.
The papers are presented in sections that accord with the conference's seven sessions, which mores specifically covered potential oncogenicity
of cellular DNA; potential oncogenicity
of viruses latent in cells; routine adventitious agent tests and the possibility of replacing in vivo methods, the level of assurance provided by guidelines, particularly the International Conference on Harmonization's Q5A and Q5D; experience with novel cell lines; bovine and porcine viruses; and bovine spongiform encephalopathy as a potential contaminant of cell substrates.
Results of a two-year chronic toxicity and oncogenicity
study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats.
Preservation of the vir gene region is vital for success, but removal of bacterial oncogenicity
genes (onc) controlling hormones is necessary to form such "disarmed" vectors.