opsonin


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Related to opsonin: opsonization, Cytokines

op·so·nin

 (ŏp′sə-nĭn)
n.
A substance, such as an antibody or complement protein, that binds to a bacterium or other pathogen and causes it to become more susceptible to the action of phagocytes.

[Latin opsōnāre, to buy provisions (from Greek opsōnein, from opson, condiment, delicacy; see epi in Indo-European roots) + -in.]

opsonin

(ˈɒpsənɪn)
n
(Biochemistry) a constituent of blood serum that renders invading bacteria more susceptible to ingestion by phagocytes in the serum
[C20: from Greek opsōnion victuals]
opsonic adj

op•so•nin

(ˈɒp sə nɪn)

n.
any of several constituents of blood serum, as an antibody or complement, that make invading microorganisms more susceptible to destruction by phagocytes.
[1900–05; < Latin opsōn(ium) victuals]
op•son•ic (ɒpˈsɒn ɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.opsonin - an antibody in blood serum that attaches to invading microorganisms and other antigens to make them more susceptible to the action of phagocytes
blood serum, serum - an amber, watery fluid, rich in proteins, that separates out when blood coagulates
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
Translations
opsonina

op·so·nin

n. opsonina, anticuerpo que al combinarse con un antígeno hace que éste sea más suceptible a los fagocitos.
References in periodicals archive ?
Key to the technology is a genetically engineered protein that is based on a naturally occurring human opsonin protein called Mannose Binding Lectin (MBL).
Activation of complement yields a variety of opsonin molecules that can rapidly coat bacterial surfaces, which interact with complement receptors on neutrophils to facilitate phagocytosis.
The team will work to develop manufacturing and integration strategies for its core pathogen-binding opsonin and Spleen-on-a-Chip fluidic separation technologies, as well as a novel coating technology called "SLIPS," which is a super-hydrophobic coating inspired from the slippery surface of a pitcher plant that repels nearly any material it contacts.
The bioactivity of lectin may appear to function as a pattern recognition protein specific for Gram-negative and acid-fast bacteria through its interaction with Lipopolysaccharide (LPS), and also as an opsonin to increase the efficiency of hemocyte phagocytosis.
Another new finding was that when CRP was allowed to interact with human LOX-1 in vitro, complement was activated (as measured by the generation of the opsonin C3d).
And although Ridgeon informs Sir Patrick in the play's opening scene that the test for the proper opsonin level is a simple matter, by the end of act 3 he deliberately neglects to communicate this vital piece of information to B.