The effector functions of the IgG subclasses are usually opsonization
and complement activation, and activation of inflammatory cells through Fc-gamma receptors.
Inhibition of complement-mediated opsonization
and phagocytosis of Streptococcus pyogenes by D fragments of fibrinogen and fibrin bound to cell surface M protein.
These cells are polymorphonuclear leukocytes which have capability to phagocyte the bare nuclei of other leukocytes with the help of auto antibodies, thus providing opsonization
to the liberated nuclear material of the target cell.
Scallop LGBP was shown to be expressed in hemocytes, exerting agglutination activity against various Gram-negative and -positive bacteria, as well as fungi, suggesting a role in pathogen recognition and opsonization
(Yang et al.
G6PD deficiency is known to exert antimalarial protection via enhanced opsonization
and phagocytosis of rings, the early forms of the parasite (Ayi et al.
It is clear from the above observations that aflatoxin caused severe immuno-suppression due to reduction in phagocytic activity of blood monocytes, depressed complement activity, hence depressed opsonization
and phagocytic activity.
None of the asymptomatic isolates showed more than 50 per cent opsonization
Cell-mediated immunity in arthropods: hematopoiesis, coagulation, melanization and opsonization
The second response cell to migrate to the wound, the neutrophil, is responsible for debris scavenging, complement-mediated opsonization
of bacteria, and bacteria destruction via oxidative burst mechanisms (i.
This process, which is called opsonization
, induces a series of inflammatory responses that help combat the infection.
Infected erythrocytes may also be phagocytosed by macrophages following opsonization
by immunoglobulins and/or complement components.
Among those, leukocyte chemotactic activity (20-22), leukocyte mobilization and adhesion defects (23-25), leukocyte phagocytosis and opsonization
defects (26-28) and diminished bactericidal activity are frequently mentioned (29,30).