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organophosphate nerve agent

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Noun1.organophosphate nerve agent - any of a series of nerve agents containing organophosphate compounds first synthesized by German chemists in 1936; in World War II the Germans tested them in concentration camps but not on the battlefield; Iraq is alleged to have used them against Iran and against the Kurds
nerve agent, nerve gas - a toxic gas that is inhaled or absorbed through the skin and has harmful effects on the nervous and respiratory system
GB, sarin - a highly toxic chemical nerve agent that inhibits the activity of cholinesterase
GD, soman - a nerve agent easily absorbed into the body; a lethal cholinesterase inhibitor that is highly toxic when inhaled
GA, tabun - the first known nerve agent, synthesized by German chemists in 1936; a highly toxic combustible liquid that is soluble in organic solvents and is used as a nerve gas in chemical warfare


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Organophosphates represent 50% of all insecticides used worldwide (Casida and Quistad 2004), and there is increasing likelihood of human exposures to organophosphate nerve agents such as those used in the terrorist incidents in Matsumoto and the Tokyo subway in Japan; therefore, identifying potential ameliorating therapies is critical.
The EyeMarker RTD1000 is an automated, portable, noninvasive device that in two minutes or less can assess, by measuring the pupil or retina of the eye, if an individual has been exposed to any of a series of toxins, including botulinum, organophosphate nerve agents, cyanide and carbon monoxide.
About Nerve Agents Organophosphate nerve agents, or anti-cholinesterase agents, cause toxicity by binding to and inhibiting acetylcholinesterase, an enzyme in the body that is essential for nervous system function.
 
 
 
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