osteoblast


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os·te·o·blast

 (ŏs′tē-ə-blăst′)
n.
A cell from which bone develops; a bone-forming cell.

os′te·o·blas′tic adj.

osteoblast

(ˈɒstɪəʊˌblæst)
n
(Physiology) a bone-forming cell
ˌosteoˈblastic adj

os•te•o•blast

(ˈɒs ti əˌblæst)

n.
a bone-forming cell.
[1870–75]
os`te•o•blas′tic, adj.

os·te·o·blast

(ŏs′tē-ə-blăst′)
A cell that produces the collagen needed for the development of new bone. As new bone grows and hardens, osteoblasts become embedded in the bone matrix. Once embedded, they are no longer able to secrete collagen and are called osteocytes.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.osteoblast - a cell from which bone develops
embryonic cell, formative cell - a cell of an embryo
Translations
luunemosolu

os·te·o·blast

n. osteoblasto, célula desarrollada aisladamente en una lacuna de la sustancia ósea.
References in periodicals archive ?
2006), reported that patients with radiation-induced fractures had decreased levels of bone density, and a further study reported impaired bone formation and decreased osteoblast proliferation and differentiation following radiotherapy.
By combining the applicant s and host s skills in mouse genetics, skeletal phenotyping and high-throughput techniques, with the expertise in energy homeostasis, mouse embryonic stem cell technologies and (glyco)proteomics at the Wellcome Trust Sanger Institute, we are confident to gain insight in a process that most possibly regulates osteoblast functioning and bone matrix production; this knowledge will contribute to the development of novel, urgently warranted anabolic medication to treat osteoporosis.
Multiple myeloma induced bone disease is marked by holes in the bone and intense pain due to increased osteoclast bone degradation activity and highly suppressed or absent osteoblast bone remodeling (growth) activity.
Osteocytes produce signals that affect both osteoblast and osteoclast activity, although the molecular signalling pathways involved are not well understood.
Osteogenesis is a strictly regulated developmental process, in which numerous hormones and growth factors activate osteoblast specific signaling proteins and transcription factors required for osteoblast differentiation.
ERK activation also plays an important role in osteoblast differentiation and osteoclast formation (Lai et al.
13] investigated the effects of LLLT of different wavelengths (670 nm, 780 nm and 830 nm) on osteoblast and osteosarcoma (cancerous) cells.
However, some reports have indicated that BMP2, a critical autocrine and paracrine growth factor that directs osteoblast differentiation and bone formation, plays an important role in heterotopic ossification.
Besides the above physical factors, biological factors such as cell membrane receptor [26], growth factors [15, 17] and the binding of extracellular matrix proteins might facilitate the enhanced osteoblast attachment on the scaffold surface.
The proinflammatory cytokines are thought to cause an imbalance in bone metabolism, favoring bone resorption via the induction of the receptor activator of nuclear factor-[kappa]B ligand (RANKL) and macrophage colony-stimulating factor (M-CSF) in osteoblasts (12-14) and by blocking bone formation via inhibition of osteoblast differentiation (15-17).
Orneklerin histomorfometrik analizlerinde trabektiler kemik yuzey alani, medullar kemik capi, osteoblast yuzey alam, osteoid kemik yuzey alam ve mineralize kemik yuzey alanlari incelenmistir.
Notably, the reductions in the bone formation rate, plasma osteocalcin levels, and ex vivo osteoblast gene expression 8 weeks post-ovariectomy are all returned to levels of sham-operated controls.