oxacillin


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Related to oxacillin: cloxacillin

ox·a·cil·lin

 (ŏk′sə-sĭl′ĭn)
n.
A semisynthetic penicillin, C19H19N3O5S, that is resistant to penicillinase, used in the form of its sodium salt primarily to treat infections caused by penicillinase-producing staphylococcus bacteria.

oxacillin

(ˌɒksəˈsɪlɪn)
n
(Medicine) an antibiotic drug containing penicillin
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.oxacillin - a form of penicillin resistant to penicillinase and effective against penicillin-resistant staphylococci
penicillinase-resistant antibiotic - a form of penicillin that is not rendered inactive by penicillinase
References in periodicals archive ?
Isolates from his third incident infection culture in August 2012 showed the same molecular characteristics as previous samples, but 2 different susceptibility patterns: 1 isolate was the same as previous, while another showed additional phenotypic resistance to oxacillin (MIC 4 [micro]g/mL by broth dilution), making this a borderline-resistant S.
aureus being resistant to oxacillin (MRSA) decreased from 47.
23% of hospital sites including the skin of the healthcare providers; 14% of these strains were oxacillin resistant, thus S.
It was utilized disks with 12 antibiotics of ordinary use, for the Gram positive bacteria: cefepime (COM, 30 [micro]g), ciprofloxacin (CIP, 5 [micro]g), clindamycin (CLI, 2 [micro]g), chloramphenicol (CLO, 30 gg), erythromycin (ERI, 15 [micro]g), gentamicin (GEN, 10 [micro]g), oxacillin (OXA, 1 [micro]g), penicillin G (PEN, 10 un), rifampicin (RIF, 5 [micro]g), sulfazotrim (SUT, 23.
12 The antibiotics that were used against gram-positive bacteria were (20 ug of amoxicillin + 10 ug of clavulanate), ceftazidime (30ug), cephalothin (30ug), clindamycin (2ug), erythromycin (15ug), gentamycin (10ug), oxacillin (1ug), penicillin (10ug) and vancomycin (30ug).
The antimicrobial agents tested were oxacillin, vancomycin, erythromycin, tetracycline, levofloxacin, clindamycin, trimethoprim-sulfamethoxazole, and linezolid.
The Clinical and Laboratory Standards Institute (CLSI) (4) states that the 1-[micro]g oxacillin disk diffusion (ODD) test is an effective screening method commonly used in clinical laboratories for the detection of penicillin-resistant pneumococci.
aureus isolates, classified as MRSA if found resistant to cefoxitin, methicillin, or oxacillin and as methicillin susceptible (MSSA) if susceptible to those antimicrobials.
The emergence of high level resistance to penicillin way back in 1948 followed by development and spread of the strains resistant to synthetic penicillin's (methicillin, oxacillin, and naficillin), macrolides, tetracycline, and aminoglycosides has made the therapy of Staphylococcal infections a global challenge.