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|Noun||1.||pachyderma - thickening of the skin (usually unilateral on an extremity) caused by congenital enlargement of lymph vessel and lymph vessel obstruction|
congenital disease, genetic abnormality, genetic defect, genetic disease, genetic disorder, hereditary condition, hereditary disease, inherited disease, inherited disorder - a disease or disorder that is inherited genetically
elephantiasis - hypertrophy of certain body parts (usually legs and scrotum); the end state of the disease filariasis
n. paquidermia. V.: elephantiasis