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palytoxin

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palytoxin  (pl-tksn)
An extremely powerful toxin occurring in corals of the genus Palythoa of the South Pacific. Palytoxin disrupts the flow of ions across cell membranes and is the most potent known naturally occurring poison, being rapidly fatal to humans in doses of 4 micrograms. One of the most complex known nonprotein substances, it has more contiguous carbon atoms (115) than any other naturally occurring molecule. Chemical formula: C129H223N3O54.


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After a 60-year overview of the history and evolution of synthesis of natural products, sections on comparative design cover classics in terpenes and alkaloid synthesis, with an additional section on miscellaneous targets such as palytoxin, brevetoxin B, and indinavir.
Maths expert Simon Wilson, 60, tried to use palytoxin to make his death look like a heart attack and spare his family more pain.
Steroids & the Pill Strychnine Penicillin Longifolene Prostaglandins & Leukotrienes Vitamin B12 Erythronolide B & Erythromycin A Monensin Avermectin Amphotericin B Ginkgolide B Cyclosporin, FK506 & Rapamycin Calicheamicin g1I Palytoxin Taxol Mevacor, Zaragozic Acids & CP Molecules Brevetoxin B Ecteinascidin 743 Epothilones Resiniferatoxin Vancomycin Thiostrepton Small Molecule Drugs Biologics For more information, visit http://www.
 
 
 
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