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pancreatic fibrosis

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Noun1.pancreatic fibrosis - the most common congenital disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
fibrosis - development of excess fibrous connective tissue in an organ


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5-fold increase above normal in chronic pancreatitis, a disease where CTGF over-expression is associated with pancreatic fibrosis.
[1] According to our previous study,[2] pancreatic fibrosis associated with alcohol abuse can show any fibrosis pattern according to Martin's 3 main patterns of pancreatic fibroatrophic states[3]: (1) predominantly intralobular sclerosis, which is always homogenous and diffuse; (2) predominantly perilobular sclerosis, with a cirrhosis-like aspect but which is irregular and sometimes patchy; and (3) mixed intralobular and perilobular sclerosis, often homogenously distributed in the gland.
 
 
 
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