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Synera(TM) is contraindicated in patients with a known history of sensitivity to lidocaine, tetracaine, local anesthetics of the amide or ester type, hypersensitivity to paraaminobenzoic acid (PABA), or sensitivity to any other component of the product.
The explanation of the effectiveness of these vegetarian diets lies in the fact that patients do not consume food containing all the potential factors which promote cell growth, in particular they do not simultaneously consume the nine essential amino acids (Valin, Isoleucin, Leucin, Lisin, Metionin, Hystidine, Tryphtophan, Phenylalanine, Treonine), nucleic acids (DNA, RNA), vitamin B12, folic acid and also paraaminobenzoic acid [PABA].
Interestingly, the patient failed to respond to sulfa drugs and penicillin but showed clinical improvement with paraaminobenzoic acid, an agent then used in the treatment of rickettsial diseases.