Relying on differences in clinical presentation to guide patient selection for clinical trials is put forward as a possible way to enhance the chance of observing a therapeutic effect, a suggestion that is echoed by neurologists treating traumatic brain injury (TBI) patients, a neurological condition with similarly complex pathophysiological
This project will potentially reveal the integral mechanisms of intestinal epithelial repair following damage, the pathophysiological
impact of epigenetic modifiers in IBD, and provide a new framework for assessing the aetiology and the onset of IBD.
Included in this definition is the cascade of pathophysiological
events that lead to progressive worsening of the initial injury, such as intracranial haemorrhage and cerebral oedema.
Our findings that prolonged oxygen desaturation, shorter sleep time and higher heart rate were associated with diabetes are consistent with the pathophysiological
mechanisms thought to underlie the relationship between OSA and diabetes," he stated.
Meeting attendees will evaluate management of PKU, interpret its pathophysiological
insights, and compare ways to counteract neurocognitive repercussions for patients.
And, instead of focusing on "the higher-order syndrome" of mania, highlighting these subdimensions might help resolve discrepancies in results from pathophysiologic studies, since different facets of mania might reflect different pathophysiological
processes, the researchers noted.
2] is as important for understanding numerous developmental and pathophysiological
processes in men as it is in women.
Because the three distinct patterns of obesity development were accompanied by different changes over time in insulin resistance and other risk factors for heart disease and diabetes, the authors conclude that "type 2 diabetes is a not a single disease entity, but rather a heterogeneous disease with different pathophysiological
pathways depending on the level and development of obesity.
A consultant for the glaucoma team at Moorfields Eye Hospital, Richard Wormald, warned that the announcement had the potential to "cause a lot of alarm" adding, "there's actually no plausible, pathophysiological
mechanism whereby oral contraceptives would cause glaucoma.
At the annual meeting of the AMA House of Delegates, it voted 276-181 to support a resolution that was brought forward by several specialty organizations that called on the AMA to "recognize obesity as a disease state with multiple pathophysiological
aspects requiring a range of interventions to advance obesity treatment and prevention.
Despite this evidence, some pathophysiological
mechanisms remain to be clarified.
Therefore, it is important to measure the circulation intact FGF-21 level in the assessment of the physiological and pathophysiological