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penicillinase
(redirected from penicillinases)

    Also found in: Medical, Encyclopedia 0.01 sec.
pen·i·cil·lin·ase  (pn-sl-ns)
n.
Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and inactivate penicillin. They are used in medicine to treat allergic reactions to penicillin. Also called beta-lactamase.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.penicillinase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
beta-lactamase
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
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Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
REPEAT/FDA Approves New Indication for INVANZ(R) (ertapenem) for the ... by Business Wire
Postulated resistance mechanisms include overproduction of conventional penicillinases, production of an inducible, plasmid-mediated, membrane-bound methicillinase, and in some cases, point mutations of penicillin-binding-proteins (4).
Community case of methicillin-resistant Staphylococcus aureus ... by Nelson, Lee; Cockram, Clive S.; Lui, Grace; Lam, Rebecca; Lam, Edman; Lai, Raymond; Ip, Margaret / Emerging Infectious Diseases
Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
FDA Approves New Indication for INVANZ(R) (ertapenem) for the ... by Business Wire
 
 
 
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