pen·i·cil·lin·ase (p n  -sl -n s)n. Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and inactivate penicillin. They are used in medicine to treat allergic reactions to penicillin. Also called beta-lactamase. |
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| Noun | 1. | penicillinase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions |
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