pentylenetetrazol


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Related to pentylenetetrazol: Metrazol

pen·tyl·ene·tet·ra·zol

 (pĕn′tə-lēn′tĕt′rə-zôl′, -zōl′, -zŏl′)
n.
A drug, C6H10N4, that is a central nervous system and respiratory stimulant, used experimentally primarily to induce seizures for pharmaceutical research.

pentylenetetrazol

(ˌpɛntɪliːnˈtɛtrəˌzɒl)
n
(Elements & Compounds) a white crystalline water-soluble substance with a bitter taste, used in medicine to stimulate the central nervous system. Formula: C6H10N4
[C20: from penta-methylene-tetrazole]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pentylenetetrazol - a drug used as a circulatory and respiratory stimulant; larger doses cause convulsions in shock therapy; Metrazol is a trademark
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
References in periodicals archive ?
Naloxone ameliorates the learning deficit induced by pentylenetetrazol kindling in rats.
Regional excitatory and inhibitory amino acid concentrations in pentylenetetrazol kindling and kindled rat brain.
Diazepam-its effects on the development of pentylenetetrazol kindling, related learning impairments, and neuronal cell loss.
28] Woodbury and Woodbury suggested that vagus stimulation may act by increasing release of glycine or gamma-amino-butyric acid, because seizures induced by both pentylenetetrazol and strychnine can be blocked by vagus stimulation.
Central nervous system stimulants: Strychnine, picrotoxin, pentylenetetrazol, and miscellaneous agents (Doxapran, Nikethamide, Methylphenidate).
In the pentylenetetrazol (PTZ) test performed in rats, EHT 0202 increased the doses of PTZ required to induce clonic and tonic convulsions, as well as death.